Title:
【発明の名称】選択された透過性を有する置換非対称シアニン色素
Document Type and Number:
Japanese Patent JPH09507879
Kind Code:
A
Abstract:
The invention describes the preparation and use of fluorescent stains for nucleic acids derived from unsymmetrical cyanine dyes comprising a substituted benzazolium ring system linked by a methine bridge to a pyridinium or quinolinium ring system having at least one substituent on the pyridinium or quinolinium ring that contains a heteroatom. The presence of the heteroatom-containing substituent results in higher sensitivity to oligonucleotides and larger nucleic acid polymers in a wide range of cells and gels, and for use in analysis of cell structure, membrane integrity or function.
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Inventors:
Yue Stephen Tea.
Singer, Victoria El.
Ross, Bruce El.
Moser, Thomas Jay.
Millard, Paul Jay.
Jones, Laurie Jay.
Gin, Kiokui
How Grand, Richard P.
Port, martin
Singer, Victoria El.
Ross, Bruce El.
Moser, Thomas Jay.
Millard, Paul Jay.
Jones, Laurie Jay.
Gin, Kiokui
How Grand, Richard P.
Port, martin
Application Number:
JP51468995A
Publication Date:
August 12, 1997
Filing Date:
October 27, 1995
Export Citation:
Assignee:
Molecular Probes, Incorporated
International Classes:
G01N33/48; C07D215/18; C07D413/06; C07D417/06; C07D417/14; C09B23/00; C09B23/02; C12Q1/68; G01N21/76; G01N33/58; (IPC1-7): C09B23/00; C07D413/06; C07D417/06; C07D417/14; G01N21/76; G01N33/48; G01N33/58
Attorney, Agent or Firm:
Shusaku Yamamoto