Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
【発明の名称】二座のメタロプロテアーゼ阻害剤
Document Type and Number:
Japanese Patent JP2000516954
Kind Code:
A
Abstract:
The invention provides compounds which are useful as inhibitors of metalloproteases, and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the present invention relates to a compound having a structure according to Formula (I) as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable alkoxyamide, ester, acyloxyamide, or imide thereof. Also disclosed are compounds, pharmaceutical compositions and methods of treating diseases characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.

Inventors:
Almstead, Neil, Gregory.
De, Wiswanus.
Bradley, Rinma, Sandler.
Garrett, Gary, Stephen.
Merlin, John, Emory, Second.
McKever, John, Macmillan.
One, Chi.
Taiwo, Jeetunde, Orabishi.
Application Number:
JP51171498A
Publication Date:
December 19, 2000
Filing Date:
August 22, 1997
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
THE PROCTER & GAMBLE COMPANY
International Classes:
A61K8/00; A61K8/49; A61K31/395; A61K31/40; A61K31/4439; A61K31/445; A61K31/454; A61K31/5377; A61P1/02; A61P9/00; A61P17/00; A61P19/08; A61P27/02; A61P29/00; A61P43/00; A61Q11/00; C07D207/36; C07D207/48; C07D211/96; C07D213/16; C07D401/04; A23G4/00; C07D401/12; C07D401/14; C07D403/04; C07D417/04; C07D417/06; C07D417/12; C07D417/14; (IPC1-7): C07D207/48; A61K7/16; A61K31/40; A61K31/4439; A61K31/445; A61K31/454; A61K31/5377; A61P1/02; A61P9/00; A61P17/00; A61P19/08; A61P27/02; A61P29/00; A61P43/00; C07D211/96; C07D401/12; C07D403/04; C07D417/04; C07D417/06; C07D417/12
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)