Intraventricular drug delivery system to improve outcomes after brain injury affecting cerebral blood flow

Title:

Intraventricular drug delivery system to improve outcomes after brain injury affecting cerebral blood flow

Document Type and Number:

Japanese Patent JP6336899

Kind Code:

B2

Abstract:

The described invention provides a flowable sustained release microparticulate composition effective to improve cerebral perfusion and to treat a delayed complication of a brain injury mediated by decreased cerebral perfusion that deposits blood in a subarachnoid space of the brain. The described invention also provides a method for preparing a flowable sustained release microparticulate composition.

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Inventors:

McDonald's Earl Loch
Reutner Brian A

Application Number:

JP2014503978A

Publication Date:

June 06, 2018

Filing Date:

April 05, 2012

Export Citation:

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Assignee:

Edge Therapeutics, Inc.

International Classes:

A61K31/4422; A61K9/10; A61K31/4545; A61K31/496; A61K45/00; A61K47/34; A61M5/178; A61P7/02; A61P9/00; A61P9/10; A61P43/00

Domestic Patent References:

JP2010529205A
JP2004105234A
JP2000070366A

Foreign References:

US20040105888
WO2001047571A2

Attorney, Agent or Firm:

Takaki Nishijima
Disciple Maru Ken
Shinichiro Tanaka
Atsushi Hakoda
Kenji Asai
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori

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