Title:
ＭＡＬＤＩ質量分析用マトリックス及びその製法並びにそれを用いた質量分析法
Document Type and Number:
Japanese Patent JP6593689
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a production method of particles having ultrafine rugged shape and being usable as matrix promoting laser desorption ionization, and a mass spectrometry using the particles.SOLUTION: An ultrafine rugged surface of a particle is used as a nanoscale reaction field for holding, rapid heating, and ionizing of an analyte. The particle has an ultrafine rugged surface with a depth range of 1 to 20 nm, easily enabling a nano-level mixed state of the analyte only by applying the analyte on the particle surface. Further, laser radiation onto nanocrystals surrounding the particle efficiently vaporizes and ionizes the analyte.SELECTED DRAWING: Figure 1
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Inventors:
Kazuya Ohiro
Masataka Otani
Masataka Otani
Application Number:
JP2015168349A
Publication Date:
October 23, 2019
Filing Date:
August 27, 2015
Export Citation:
Assignee:
Kochi Public University Corporation
International Classes:
G01N27/62; B22F1/00; B22F9/24; B82Y30/00; C01G23/053; C01G49/00; C01G51/00; C01G53/00; H01J49/16
Domestic Patent References:
| JP2009009811A | ||||
| JP2011027477A | ||||
| JP2013245137A | ||||
| JP2013257332A | ||||
| JP2006233252A |
Other References:
Martin Schuerenberg et al.,Laser Desorption/Ionization Mass Spectrometry of Peptides and Proteins with Particle Suspension Matrixes,Analytical Chemistry,1999年,71,pages 221-229
Attorney, Agent or Firm:
Kazuhiro Kiyohara