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Title:
METHODS AND COMPOSITIONS FOR INHIBITING FUNCTION OF POLYNUCLEOTIDE SEQUENCES
Document Type and Number:
Japanese Patent JP2007236391
Kind Code:
A
Abstract:

To provide a polynucleotide composition having an inhibitory effect to a specific polynucleotide sequence being in a mammalian cell.

The present invention provides a partially double-stranded RNA molecule having a plurality of targets and comprising two or more different double-stranded RNA sequences which are substantially homologous and complementary to two or more sequences of at least one target gene.

COPYRIGHT: (C)2007,JPO&INPIT


Inventors:
PACHUK CATHERINE
SATISHCHANDRAN C
Application Number:
JP2007098266A
Publication Date:
September 20, 2007
Filing Date:
April 04, 2007
Export Citation:
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Assignee:
WYETH CORP
International Classes:
C12N15/09; A61K31/7088; A61K31/7105; A61K35/74; A61K35/76; A61K39/00; A61K47/22; A61K48/00; A61P31/04; A61P31/12; A61P35/00; C12N15/11; C12N15/113; C12N15/63; C12P19/34; A61K38/00
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita