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Title:
MICROORGANISMS OR FRACTIONS THEREOF CAPABLE OF ACTIVATING CELLULAR IMMUNITY AGAINST CARBOHYDRATES
Document Type and Number:
Japanese Patent JP2015134813
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide microorganisms or fractions thereof capable of activating cellular immunity against carbohydrates.SOLUTION: The invention relates to the field of prevention and treatment of tumors and gastrointestinal disorders. More specifically, the invention relates to prevention and treatment of Core-1 positive carcinomas. The invention relates to Coreotics and methods for preparing it, and methods for preventing and treating core-1 positive disorders using it. The invention provides nutraceuticals and pharmaceutical compositions comprising the Core-1 positive microorganism and fractions thereof suitable for inducing immune responses against Core-1, tumor cells carrying Core-1 and molecules comprising Core-1.

Inventors:
GOLETZ STEFFEN
PHILIPPE ULSEMER
ANJA LOFFLER
Application Number:
JP2015075105A
Publication Date:
July 27, 2015
Filing Date:
April 01, 2015
Export Citation:
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Assignee:
GLYCOTOPE GMBH
International Classes:
A61K35/74; A23L1/28; A61K35/17; A61K39/00; A61P35/00; A61P35/02; A61P35/04; A61P37/04; C12N1/00; C12N1/20; C12N5/0783; C12N5/0784; C12Q1/02; G01N33/15; G01N33/50; G01N33/53; G01N33/536; G01N33/543; G01N33/574
Foreign References:
WO2006012616A22006-02-02
Other References:
JPN6013003156; British Journal of Haematology Vol.47, 1981, p.453-460
JPN6013003158; J. Mol. Med. Vol.75, 1997, p.594-602
JPN5010000862; GOLETZ S: 'THOMSEN-FRIEDENREICH ANTIGEN:THE HIDDEN TUMOR ANTIGEN' ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY V535, 2003, P147-162
JPN5009019425; CLAUSEN H: MOLECULAR IMMUNOLOGY V25 N2, 1988, P199-204
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita