NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF

Title:

NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF

Document Type and Number:

Japanese Patent JP2020062050

Kind Code:

A

Abstract:

To provide neuroactive steroids, compositions, and uses thereof.SOLUTION: Provided are methods of evaluating or treating a patient, e.g., a patient having a disorder described herein, comprising: a) optionally, acquiring a patient sample; and b) acquiring an evaluation of the sample and/or evaluating the sample for an alteration in the level of 24(S)-hydroxycholesterol compared with a reference standard.SELECTED DRAWING: None

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Inventors:

KIRAN REDDY
JAMES DOHERTY

Application Number:

JP2020008895A

Publication Date:

April 23, 2020

Filing Date:

January 23, 2020

Export Citation:

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Assignee:

SAGE THERAPEUTICS INC

International Classes:

C12Q1/02; A61K31/575; A61K45/00; A61K45/06; A61P25/28; A61P43/00; C07J1/00; C07J3/00; C07J9/00

Domestic Patent References:

JP2005508368A

2005-03-31

Foreign References:

US20080269183A1	2008-10-30
US20120115169A1	2012-05-10
WO2013036835A1	2013-03-14

Other References:

BMC NEUROL. (2011) VOL.11, 121, JPN6017045798, ISSN: 0004917331
NEUROSCI. LETT. (2009) VOL.462, ISSUE 1, P.89-93, JPN6018042898, ISSN: 0004917332
NEUROREPORT (2000) VOL.11, NO.9, P.1959-1962, JPN6018042900, ISSN: 0004917333

Attorney, Agent or Firm:

Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto

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