To provide a new protein having transport activity of monocarboxylic acids, amino acids, etc., a polynucleotide encoding the protein, a method for screening a compound promoting or inhibiting the activity of the protein or the expression of the protein gene, a compound obtained by the screening method, etc.
The protein is useful e.g. as a diagnostic marker for respiratory diseases, renal diseases, central nervous diseases, metabolic acidosis, muscular diseases, inflammatory diseases, autoimmune diseases, allergic diseases, splenic diseases, immunoinsufficiency, hepatic diseases, digestive tract diseases, reproductive system diseases, cancers, etc. The protein and the compound produced by the screening method with the protein and promoting or inhibiting the activity of the protein can be used as a safe medicine such as an agent for the prevention and treatment of the above diseases, an antirejection agent after an organ transplant operation, etc.
SAGIYA YOJI
HIKICHI YUKIKO
NISHIMURA ATSUSHI
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