To provide easily and comfortably administered dosage formulations of effective colonic purgatives.
There are provided orally administered colonic purgative formulations and methods of their use for effecting partial or complete purgation of the colon in mammals. The formulations consist of non-aqueous admixtures of a purgative salt selected from the group consisting of Mg3(PO4)2, MgHPO4, Mg(H2PO4)2, MgSO4, MgCl2, Na2SO4, sodium tartrate, potassium tartrate, magnesium tartrate, and mixtures thereof, administered in tablet or capsule form in purgative effective concentrations. Preferred embodiments make use of at least one or more magnesium phosphate salts, more preferably dibasic magnesium phosphate; other preferred embodiments include the addition of binders, dispersants and buffers which do not adversely affect osmolality or effectiveness of the purgative formulations.
WILLIAMS TAFFY J
KRELL ROBERT D
CRAIG A ARONCHICH
Takaaki Yasumura
Natsuki Morishita
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