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Title:
NOVEL BINDING DOMAIN-CONTAINING POLYPEPTIDE AND USE THEREOF
Document Type and Number:
Japanese Patent JP2023052563
Kind Code:
A
Abstract:
To provide binding substances that bind to a target of interest with a high degree of specificity.SOLUTION: A polypeptide for binding to a target of interest comprises an amino acid sequence comprising the following sequence, is derived from modifications to the amino acid sequence consisting of a particular sequence, and specifically binds to the target of interest. The specific binding between the polypeptide and the target of interest is stronger than the binding between the polypeptide of the amino acid sequence consisting of the particular sequence to the target of interest.SELECTED DRAWING: None

Inventors:
lafleur david william
Hilbert David Em.
Application Number:
JP2023007753A
Publication Date:
April 11, 2023
Filing Date:
January 23, 2023
Export Citation:
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Assignee:
Subdomain Limited Liability Company
Acerx Inc.
International Classes:
C12N15/13; A61K35/17; A61K48/00; A61P35/00; A61P37/02; A61P43/00; C07K14/725; C07K16/28; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N7/01; C12N15/12; C12N15/62; C12N15/63
Domestic Patent References:
JP6871232B22021-05-12
Other References:
TRENDS BIOTECHNOL., vol. 23, no. 10, JPN6020014590, 2005, pages 514 - 522, ISSN: 0005228726
FEBS J., vol. 275, JPN6020014592, 2008, pages 2668 - 2676, ISSN: 0005228727
ANNU. REV. PHARMACOL. TOXICOL., vol. 55, JPN6020014596, 2015, pages 489 - 511, ISSN: 0005228728
PROC. NATL. ACAD. SCI., vol. 96, JPN6021009000, 1999, pages 5486 - 5491, ISSN: 0005228729
Attorney, Agent or Firm:
Shimizu Hatsushi
Masao Haruna
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto