Title:
NOVEL FORMULATIONS OF VOLATILE ANESTHETICS AND METHODS OF USE THEREOF FOR REDUCING INFLAMMATION
Document Type and Number:
Japanese Patent JP2016047834
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide novel formulations of volatile anesthetics and methods of use for treating an inflammation or wound.SOLUTION: In a composition, a component of an emulsion comprising a lipid, such as soybean oil or olive oil, is a solution comprising: an effective amount of a volatile anesthetic, such as isoflurane, halothane, enflurane or sevoflurane, dissolved in an aqueous solution; and a solvent to reduce the volatility, such as dimethyl sulfoxide, N-methyl-2-pyrrolidone, dimethylformamide, dimethylacetamide or ethanol. A method comprises administering the composition via a topical, intrathecal, epidural, transdermal, topical, oral, intra-articular, mucosal, buccal, rectal, vaginal, intramuscular, intravesical or subcutaneous route.SELECTED DRAWING: Figure 1
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Inventors:
DANGUOLE SPAKEVICIUS
HATICE OZSOY
HATICE OZSOY
Application Number:
JP2015212498A
Publication Date:
April 07, 2016
Filing Date:
October 29, 2015
Export Citation:
Assignee:
UNIV TEXAS
International Classes:
A61K45/00; A61K9/107; A61K9/127; A61K31/02; A61K31/08; A61K47/10; A61K47/16; A61K47/20; A61K47/22; A61K47/24; A61K47/34; A61K47/44; A61P1/04; A61P9/00; A61P13/08; A61P13/10; A61P17/02; A61P19/02; A61P21/00; A61P23/02; A61P29/00
Domestic Patent References:
JP2006504740A | 2006-02-09 | |||
JPS60501557A | 1985-09-19 | |||
JP2003520769A | 2003-07-08 | |||
JP2005539004A | 2005-12-22 | |||
JPH10251142A | 1998-09-22 |
Foreign References:
WO2008036858A2 | 2008-03-27 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
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