Title:
NUCLEIC ACID SEGMENT ENCODING CHONDROITIN SYNTHASE, RECOMBINANT VECTOR COMPOSED OF SEGMENT THEREOF, RECOMBINANT HOST CELL COMPOSED OF VECTOR THEREOF AND METHOD FOR PRODUCING CHONDROITIN POLYMER BY USING HOST CELL THEREOF
Document Type and Number:
Japanese Patent JP2008283974
Kind Code:
A
Abstract:
To provide a nucleic acid segment encoding a new HAS (hyaluronate synthase) relating to Pasteurella multocida which is an agricultural pathogen of poultry, domestic animals, sheep and pig.
There provided are the nucleic acid segment having a coding region segment encoding an enzymatically active bacterial multocida hyaluronate synthase (PmHAS), the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product, and the use of the PmHAS in constructing "knock-out" mutant strains of P. multocida for use in vaccinations. The use of the PmHAS in diagnostic tests in the field determinations of P. multocida infection of livestocks is also provided.
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Inventors:
DEANGELIS PAUL (US)
Application Number:
JP2008146037A
Publication Date:
November 27, 2008
Filing Date:
June 03, 2008
Export Citation:
Assignee:
UNIV OKLAHOMA STATE (US)
International Classes:
C12N15/09; A61K39/00; G01N33/48; A61K39/102; A61K47/36; A61P31/04; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/00; C12N9/10; C12P19/04; C12P19/26; C12Q1/02; C12Q1/68; G01N33/53; G01N33/566
Attorney, Agent or Firm:
Yasuo Ishikawa