Title:
OBJECTIVE DIAGNOSTIC METHOD FOR SCHIZOPHRENIA USING GENE EXPRESSION AS INDEX
Document Type and Number:
Japanese Patent JP3507884
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide an objective diagnostic method for schizophrenia using a gene expression as an index since a diagnostic method for schizophrenia is defined only by a psychological symptom study such as a delusion type, a dissolution type, a tension type or a discrimination incapability type even in DSMIV of the latest diagnostic criterion, the final diagnosis cannot but depend upon the subjectivity of a physician in charge and diagnostic accuracy is not sufficient.
SOLUTION: This method diagnoses whether a testee is infected with schizophrenia or not and is provided with a process for collecting a specimen containing a nucleic acid and/or a protein from the testee, a process for determining a protein described in a table 1 and a table 2 (reference to the specification) or its fragment and/or at least one nucleic acid selected from the group consisting of a nucleic acid shown by a GenBank register number in the parentheses encoding the protein or its fragment and a nucleic acid complementary to the nucleic acid and a process for diagnosing whether the testee is infected with schizophrenia or not by using a determined value of at least one of the protein or its fragment or the nucleic acid as an index.
More Like This:
Inventors:
Naba, Hiroyuki
Takahashi, Hitoshi
Iritani, Shuji
Takahashi, Hitoshi
Iritani, Shuji
Application Number:
JP2000061775A
Publication Date:
March 15, 2004
Filing Date:
March 07, 2000
Export Citation:
Assignee:
Univ, Niigata
International Classes:
G01N33/50; C12N15/09; C12Q1/68; G01N33/15; G01N33/53; G01N33/68; G01N37/00; (IPC1-7): C12N15/09; C12Q1/68; G01N33/15; G01N33/50; G01N33/53
Other References:
Ｐｒｏｃ．Ｎａｔｌ．Ａｃａｄ．Ｓｃｉ．ＵＳＡ，Ｖｏｌ．８８（１９９１），ｐ．１０２３７−１０２４１
Ｓｏｃｉｅｔｙ ｆｏｒ Ｎｅｕｒｏｓｃｉｅｎｃｅ Ａｂｓｔｒａｃｔｓ，Ｖｏｌ．２３，Ｎｏ．１−２（１９９７），ｐ．２２０１
Ｓｏｃｉｅｔｙ ｆｏｒ Ｎｅｕｒｏｓｃｉｅｎｃｅ Ａｂｓｔｒａｃｔｓ，Ｖｏｌ．２３，Ｎｏ．１−２（１９９７），ｐ．２２０１
Attorney, Agent or Firm:
鈴江 武彦 （外５名）