Title:
PRODUCTION OF ACETYLENE DERIVATIVE
Document Type and Number:
Japanese Patent JP3526777
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To produce the subject derivative in good yield in one process under mild reactional conditions by reacting a ketone compound having 2 α hydrogens with a bis-disubstituted amino-difluoromethane or a fluoroformamidinium halogenide.
SOLUTION: (A) A compound having a skeleton represented by formula I in the molecule is reacted with (B) a compound represented by formula II (R1 to R4 are each a 1-6C alkyl, an aryl or the like) or a compound represented by formula III (X1 is Cl, Br or I) to thereby produce (A) an acetylene derivative. The component A is preferably a compound represented by formula IV (R5 and R6 are each H, an alkyl, an aralkyl or the like) and the component C is the acetylene compound represented by formula V (R and R' are each the same as R5 and R6). For example, acetophenone can be used as the component A and reacted with 2,2-difluoro-1,3-dimethylimidazolidine used as the component B in acetonitrile used as a solvent to afford phenylacetylene.
Inventors:
Sonoda, Hiroshi
Okada, Kazunari
Goto, Kenichi
Fukumura, Takanori
Naruse, Junko
Hayashi, Hidetoshi
Nagata, Teruyuki
Takahashi, Akira
Okada, Kazunari
Goto, Kenichi
Fukumura, Takanori
Naruse, Junko
Hayashi, Hidetoshi
Nagata, Teruyuki
Takahashi, Akira
Application Number:
JP8537599A
Publication Date:
May 17, 2004
Filing Date:
March 29, 1999
Export Citation:
Assignee:
MITSUI CHEMICALS INC
International Classes:
C07C1/207; C07C1/24; C07C11/22; C07C15/48; C07C15/54; C07C37/00; C07C39/18; C07C201/12; C07C205/06; (IPC1-7): C07C1/207; C07C1/24; C07C11/22; C07C15/48; C07C15/54; C07C37/00; C07C39/18; C07C201/12; C07C205/06
Attorney, Agent or Firm:
苗村 新一 （外１名）