Title:
PRODUCTION OF COMPOSITE CARBOHYDRATE
Document Type and Number:
Japanese Patent JP3732871
Kind Code:
B2
Abstract:
PURPOSE: To obtain in high yield a sialo-composite carbohydrate useful as e.g. a medicine by making endoglycosidase act on a composite carbohydrate composed of a sialic acid-contg. sugar chain to directly transfer the sialosugar chain to a sugar chain receptor.
CONSTITUTION: Endoglycosidase is made to act on a composite carbohydrate, as a sugar chain donor, composed of a sialic acid-contg. sugar chain to directly transfer the sialosugar chain to a sugar chain receptor without detaching the sialic acid, thus easily affording the objective sialo-composite carbohydrate. Use of a physiologically active peptide having N-acetylglucosamine residue as the sugar chain receptor can synthesize a desired sialo-composite glycopeptide.
Inventors:
Katsuji Haneda
Toshiyuki Inazu
Toshiyuki Inazu
Application Number:
JP17037895A
Publication Date:
January 11, 2006
Filing Date:
June 13, 1995
Export Citation:
Assignee:
Noguchi Research Institute
International Classes:
C12N9/42; C12P19/26; A61K31/7012; A61K31/702; A61K31/715; A61P43/00; C07H3/06; C07H7/027; (IPC1-7): C12P19/26; C07H3/06; C07H7/027; C12N9/42; //A61K31/725
Domestic Patent References:
| JP7059587A | ||||
| JP5064594A | ||||
| JP11505263A |
Other References:
J.Biol.Chem.,(1995),270(7),p3094-3099