PYRIDOXINE DERIVATIVE AND BLOOD PLATELET COAGULATION INHIBITOR CONTAINING THE SAME

Title:

PYRIDOXINE DERIVATIVE AND BLOOD PLATELET COAGULATION INHIBITOR CONTAINING THE SAME

Document Type and Number:

Japanese Patent JPS59199674

Kind Code:

A

Abstract:

NEW MATERIAL:A pyridoxine derivative of formula I (R is acyl derived from triene or pentaene-higher fatty acid).

EXAMPLE: 2-Methyl-3-hydroxy-4-hydroxymethyl-5-(9, 12, 15-octadecatrienoyl)oxymethylpyridine.

USE: Blood platelet coagulation inhibitor.

PREPARATION: The reaction between a triene- or pentaene-higher fatty acid and isopropylidene pyridoxine is conducted in the presence of a condensation reagent such as N,N'-dicyclohexyl carbodiimide, then the product is hydrolyzed to form the compound of the formula 1.

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Inventors:

WAKABAYASHI TOSHIO
ARAI JIYUNICHIROU
KATAYAMA HAJIME

Application Number:

JP7331283A

Publication Date:

November 12, 1984

Filing Date:

April 26, 1983

Export Citation:

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Assignee:

TERUMO CORP

International Classes:

C07D213/66; A61K31/44; A61K31/4418; A61P7/02; A61P35/00; C07D491/056; (IPC1-7): A61K31/44; C07D213/66; C07D491/056

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