SUBSTITUTED THIAZOLE DERIVATIVE BEARING 3-PYRIDYL GROUP, METHOD FOR PRODUCING THE SAME AND USE THEREOF

Title:

SUBSTITUTED THIAZOLE DERIVATIVE BEARING 3-PYRIDYL GROUP, METHOD FOR PRODUCING THE SAME AND USE THEREOF

Document Type and Number:

Japanese Patent JP2008266349

Kind Code:

A

Abstract:

To provide a medicinal composition that has the steroid C17,20lyase inhibiting activity, and is useful for preventing and treating prostatism or tumor such as breast cancer.

The steroid C17,20lyase inhibitor includes a compound represented by the formula (I) (wherein A1 is an aromatic hydrocarbon group which may bear a substituent or a heterocyclic group which may bear a substituent, one of A2 or A3 is H atom, a halogen atom, a 1-4 C aliphatic hydrocarbon group which may bear a substituent or a carboxy group which may be esterified, the other is an aromatic hydrocarbon group which may bear a substituent or a heterocyclic group which may bear a substituent wherein at least one of A1, A2, and A3 is 3-pyridyl group which may bear a substituent) or salt or prodrug thereof.

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Inventors:

KURODA NORITAKA
NARA TEI
HASHIGUCHI SHOHEI
TASAKA AKIHIRO
KUSAKA MASAMI
YAMAOKA MASUO
KAKO TOSHIHIRO

Application Number:

JP2008154723A

Publication Date:

November 06, 2008

Filing Date:

June 12, 2008

Export Citation:

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Assignee:

TAKEDA CHEMICAL INDUSTRIES LTD

International Classes:

C07D417/04; A61K31/4439; A61K31/4545; A61K31/4725; A61K31/506; A61K31/55; A61P5/28; A61P5/32; A61P13/08; A61P15/00; A61P15/08; A61P17/14; A61P35/00; A61P43/00; C07D417/14

Attorney, Agent or Firm:

Takashima Ichi

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