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Title:
SUPPRESSANT FOR MAILLARD REACTION
Document Type and Number:
Japanese Patent JP3872834
Kind Code:
B2
Abstract:

PROBLEM TO BE SOLVED: To obtain a medicine, comprising a flavonoid compound having the aurone skeleton as an active ingredient and having suppressing actions on the Maillard reaction.
SOLUTION: This suppressant for the Maillard reaction comprises a flavonoid compound represented by formula I, preferably maritimein represented by formula II or its salt or sulfuretin represented by formula III or its salt as an active ingredient. The suppressant for the Maillard reaction is useful for preventing and treating diseases caused by the Maillard reaction, diabetes and complications thereof, e.g. neurosis, cerebral angiopathy, peripheral circulation disorder, coronary arterial cardiopathy, arteriosclerosis, arthrosclerosis, cataract or retinopathy or diseases caused by aging, e.g. senile cataract, atherosclerosis, coronary arterial cardiopathy or cerebral angiopathy. The daily dose thereof for an adult is 10mg to 10g perorally or parenterally administered. The compounds of formula II and III are well known and usually available.


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Inventors:
Hidetoshi Takahashi
Kenichi Kimura
Makoto Yoshihama
Kazuma Shioda
Yoshinori Negishi
Kenji Seri
Application Number:
JP7087396A
Publication Date:
January 24, 2007
Filing Date:
March 04, 1996
Export Citation:
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Assignee:
Daiichi Pharmaceutical Co., Ltd.
Godo Shusei Co., Ltd.
International Classes:
A61K31/7048; C07D307/83; A61K31/34; A61K31/343; A61K31/70; A61K31/7042; A61P3/08; A61P3/10; A61P9/00; A61P9/10; A61P19/02; A61P27/12; A61P43/00; C07H17/04; C07D307/86; (IPC1-7): A61K31/70; A61K31/34; A61K31/34; C07H17/04; //C07D307/83
Domestic Patent References:
JP3232851A
JP6336430A
JP7324025A
JP5509078A
JP55040692A
Other References:
Chemical and Pharmaceutical Bulletin,1989年,Vol.37, No.7,p.1685-1970
Attorney, Agent or Firm:
Eiko Funahashi



 
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