Title:
新規なアビエタンジテルペノイド系化合物、及び榧抽出物、またはそれから分離したアビエタンジテルペノイド系化合物またはテルペノイド系化合物を有効成分とする心臓循環系疾患の予防及び治療用組成物
Document Type and Number:
Japanese Patent JP4777970
Kind Code:
B2
Abstract:
A method for treating cardiovascular disease, including hyperlipidemia and atherosclerosis, using abietane diterpenoid compound or terpenoid compound isolated from Torreya nucifera as an effective ingredient. The abietane diterpenoid compound or terpenoid compound isolated from Torreya nucifera not only excellently inhibits oxidation of low-density lipoprotein (LDL), but also effectively inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity.
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Inventors:
John, Tae Suk
Lee, Woo Sung
Kim, Hyun-Shin
Choi, Yang-kyu
Kim, Ju-ryeon
Anne, Seo Jin
Im, Kyung-run
Chan, Ki-chan
Moon, og-sun
Sung, Jun-Suk
Lee, Woo Sung
Kim, Hyun-Shin
Choi, Yang-kyu
Kim, Ju-ryeon
Anne, Seo Jin
Im, Kyung-run
Chan, Ki-chan
Moon, og-sun
Sung, Jun-Suk
Application Number:
JP2007501703A
Publication Date:
September 21, 2011
Filing Date:
February 22, 2005
Export Citation:
Assignee:
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
International Classes:
C07C43/305; A61K31/05; A61K31/075; A61K31/11; A61K36/13; A61K36/18; A61P3/06; A61P9/00; A61P9/10; C07C33/38; C07C37/00; C07C39/17; C07C43/315; C07C45/78; C07C47/45; C07C61/35
Domestic Patent References:
| JPS4631218B1 |
Attorney, Agent or Firm:
Atomi International Patent Office
Yasuo Yasutomi
Yasuo Yasutomi