Title:
血漿カリクレイン阻害薬
Document Type and Number:
Japanese Patent JP2023533519
Kind Code:
A
Abstract:
本発明は、式（Ｉ）で表される化合物、及び、１以上の化合物を含む医薬組成物、及び、血漿カリクレインを阻害することで利益を得ることができる１以上の疾患状態（これは、遺伝性血管浮腫、ブドウ膜炎、後部ブドウ膜炎、ウェット型加齢性黄斑浮腫、糖尿病性黄斑浮腫、糖尿病性網膜症及び網膜静脈閉塞症を包含する）を治療又は予防するための化合物の使用方法を提供する。化合物は、血漿カリクレインの選択的阻害剤である。【化１】TIFF2023533519000130.tif20131
More Like This:
Inventors:
Hicks, Jacqueline Dee
Quang, Longe
Jintz, Christopher Jay
Lombardo, Matthew Jay
Lopez, Jovan Alexander
Merchant, Rohan
Sharp, Philip Patrick
Wu, Chi Kai
Zhao, Qi Chang
Chen, Alan Si
Yang, Song
Bao, Jenmin
Thian, Maokang
Shane Nance, Galen Paul
Quang, Longe
Jintz, Christopher Jay
Lombardo, Matthew Jay
Lopez, Jovan Alexander
Merchant, Rohan
Sharp, Philip Patrick
Wu, Chi Kai
Zhao, Qi Chang
Chen, Alan Si
Yang, Song
Bao, Jenmin
Thian, Maokang
Shane Nance, Galen Paul
Application Number:
JP2023500332A
Publication Date:
August 03, 2023
Filing Date:
July 06, 2021
Export Citation:
Assignee:
Merck Sharp & Dome LLC
International Classes:
C07D401/14; A61K31/435; A61K31/4439; A61K31/497; A61K31/501; A61K31/506; A61K45/00; A61P1/04; A61P1/18; A61P3/10; A61P7/02; A61P9/00; A61P11/00; A61P13/12; A61P19/02; A61P25/00; A61P27/02; A61P29/00; A61P31/00; A61P35/00; C07D403/14; C07D413/14
Attorney, Agent or Firm:
Makoto Ono
Kennori Kanayama
Yoshiyuki Tsubokura
Kazuki Shigemori
Kenji Ando
Hidehiko Ichikawa
Yoshie Sakurada
Yosuke Kawasaki
Youichi Iino
Yusuke Ichikawa
Sohei Aya
Takahiro Suzuki
Yoshikazu Iwase
Yasufumi Shiroyama
Kennori Kanayama
Yoshiyuki Tsubokura
Kazuki Shigemori
Kenji Ando
Hidehiko Ichikawa
Yoshie Sakurada
Yosuke Kawasaki
Youichi Iino
Yusuke Ichikawa
Sohei Aya
Takahiro Suzuki
Yoshikazu Iwase
Yasufumi Shiroyama
Previous Patent: Device for mitigation of non-analyte derived signals
Next Patent: Device-like Overlay Metrology Targets Exhibiting Moire Effect
Next Patent: Device-like Overlay Metrology Targets Exhibiting Moire Effect