抗マラリア療法のための置換２−アルキル−１−オキソ−Ｎ−フェニル−３−ヘテロアリール−１，２，３，４−テトラヒドロイソキノリン−４−カルボキサミド

Japanese Patent JP2014524464

A

In one aspect, the invention relates to novel substituted 2-alkyl-1-oxo-N-phenyl-3-heteroaryl -1,2,3,4-tetrahydroisoquinoline-4-carboxamides; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating and/or preventing malaria. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

JP2018021074	CANNABINOID RECEPTOR MODULATOR
JP2002504909	[Title of Invention] Novel Substituted Pyrazole and Pyrazoline Compounds
JP2000516602	Title of Invention Substituted pyrimidine derivatives and their use as agents

Rodney キプリン Guy
ファンギ Chu
Wendy Ham Armand ギグムド
Day ビィッド Floyd
Spencer Knapp
Philip Stein
Steve Castro

JP2014526594A

September 22, 2014

August 24, 2012

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Cent Jude Chilled lens Research Hospital
エムエムヴィ メディシンズ Forehand Malaria ヴェンチャー MMV MEDICINES FOR MALARIA VENTURE
Latho Garth -- the -- The State University オブ New Jersey RUTGERS and THE STATE UNIVERSITY OF NEW JERSEY

C07D401/04; A61K31/4725; A61K31/506; A61K45/00; A61P33/00; A61P33/06; A61P43/00; C07D409/04; C07D417/04

JPH10501517A	1998-02-10
JP2011520951A	2011-07-21
JPH10501518A	1998-02-10
JPH10501517A	1998-02-10
JP2011520951A	2011-07-21
JPH10501518A	1998-02-10

WO2010055164A2	2010-05-20
WO2010055164A2	2010-05-20

JPN5014009948; ＧＵＩＧＵＥＭＤＥ　Ｗ　ＡＲＭＡＮＤ: ＮＡＴＵＲＥ Ｖ４６５, 20100520, Ｐ３１１-３１５
JPN5014009948; ＧＵＩＧＵＥＭＤＥ　Ｗ　ＡＲＭＡＮＤ: ＮＡＴＵＲＥ Ｖ４６５, 20100520, Ｐ３１１-３１５

Akio Konno
Inami Fruit
Takehiro Ito
Tamura 慶政

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