Title:
肝分泌型代謝制御因子阻害作用による肥満関連疾患治療剤
Document Type and Number:
Japanese Patent JP6959913
Kind Code:
B2
Abstract:
Disclosed are methods for screening a drug for treating obesity-related diseases by using the ability of candidate drugs to inhibit the function of pentraxin-4 as an index, and a pharmaceutical composition for treating obesity-related diseases comprising a pentraxin-4 inhibitor as an active ingredient. The drug screened by the above-mentioned method and the pharmaceutical composition are useful for treating obesity-related diseases, particularly for non-alcoholic steatohepatitis (NASH).
Inventors:
Yoshihiko Izumida
Nobuhiro Wada
Purple masuda
Takashi Kadowaki
Nobuhiro Wada
Purple masuda
Takashi Kadowaki
Application Number:
JP2018517100A
Publication Date:
November 05, 2021
Filing Date:
May 12, 2017
Export Citation:
Assignee:
National University Corporation Tokyo University
International Classes:
C12Q1/6897; A61K31/7088; A61K31/7105; A61K35/761; A61K39/395; A61K45/00; A61K48/00; A61P3/04; A61P3/10; C07K16/18; C12N15/11; C12N15/113; C12N15/65
Domestic Patent References:
| JP2007517021A |
Other References:
Clinica Chimica Acta,2012年,Vol.413,p.1430-1437
生物試料分析,2010年,Vol.33,p.339-346
The Journal of Immunology,2010年,Vol.184,p.5055-5064
Annual review of immunology,2005年,Vol.23,p.337-366
生物試料分析,2010年,Vol.33,p.339-346
The Journal of Immunology,2010年,Vol.184,p.5055-5064
Annual review of immunology,2005年,Vol.23,p.337-366
Attorney, Agent or Firm:
Yukitaka Nakamura
Manabu Miyajima
Mari Asano
Hiroshi Sorimachi
Manabu Miyajima
Mari Asano
Hiroshi Sorimachi
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