Title:
3-(3-ARYL/HETEROARYL-4-THIAZOLINONE)-N-ARYL/HETEROCYCLIC BENZAMIDE COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/057387
Kind Code:
A1
Abstract:
A 3-(3-Aryl/heteroaryl-4-thiazolinone)-N-aryl/heterocyclic benzamide compound, or a pharmaceutically-acceptable salt thereof, and a preparation method therefor. The compound type or a pharmaceutical composition thereof can be used to treat osteosarcoma, colorectal cancer, pancreatic cancer, leukemia, and related diseases.
Inventors:
LIU SHUNYING (CN)
DENG YAQI (CN)
NIU LI (CN)
SONG LONGLONG (CN)
NI DAN (CN)
LI ZI (CN)
HAN WANGYUJING (CN)
WEI QINGHUA (CN)
DONG SUZHEN (CN)
PI ROU (CN)
DENG YAQI (CN)
NIU LI (CN)
SONG LONGLONG (CN)
NI DAN (CN)
LI ZI (CN)
HAN WANGYUJING (CN)
WEI QINGHUA (CN)
DONG SUZHEN (CN)
PI ROU (CN)
Application Number:
PCT/CN2021/104268
Publication Date:
March 24, 2022
Filing Date:
July 02, 2021
Export Citation:
Assignee:
SHANGHAI HONGHENG BIOMEDICAL TECH CO LTD (CN)
International Classes:
A61K31/426; C07D277/14; A61K31/427; A61K31/4439; A61K31/454; A61K31/497; A61P35/00; A61P35/02; C07D277/38; C07D277/44; C07D277/56; C07D417/04
Foreign References:
| CN102786493A | 2012-11-21 | |||
| CN102653526A | 2012-09-05 |
Other References:
ZHANG TAO, LI JINGJIE, HE YUAN, YANG FEIFEI, HAO YUN, JIN WANGRUI, WU JING, SUN ZHENLIANG, LI YUNQI, CHEN YIHUA, YI ZHENGFANG, LIU: "A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer", NATURE COMMUNICATIONS, vol. 9, no. 1, 1 December 2018 (2018-12-01), pages 1 - 13, XP055912072, DOI: 10.1038/s41467-018-06179-0
WU JING, YU LINXI, YANG FEIFEI, LI JINGJIE, WANG PENG, ZHOU WENBO, QIN LIWEN, LI YUNQI, LUO JIAN, YI ZHENGFANG, LIU MINGYAO, CHEN : "Optimization of 2-(3-(arylalkyl amino carbonyl) phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives as potent antitumor growth and metastasis agents", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 80, 1 June 2014 (2014-06-01), AMSTERDAM, NL , pages 340 - 351, XP055781860, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2014.04.068
WU JING, YU LINXI, YANG FEIFEI, LI JINGJIE, WANG PENG, ZHOU WENBO, QIN LIWEN, LI YUNQI, LUO JIAN, YI ZHENGFANG, LIU MINGYAO, CHEN : "Optimization of 2-(3-(arylalkyl amino carbonyl) phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives as potent antitumor growth and metastasis agents", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 80, 1 June 2014 (2014-06-01), AMSTERDAM, NL , pages 340 - 351, XP055781860, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2014.04.068
Attorney, Agent or Firm:
MSJLAW OFFICE (CN)
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