AIEGENS FOR CANCER CELLS AND GRAM-POSITIVE BACTERIA DISCRIMINATION AND KILLING

Title:

AIEGENS FOR CANCER CELLS AND GRAM-POSITIVE BACTERIA DISCRIMINATION AND KILLING

Document Type and Number:

WIPO Patent Application WO/2018/210334

Kind Code:

A1

Abstract:

AIE luminogens as theranostic agents may be used in photodynamic therapy to selectively detect and kill cancer cells and gram-positive bacteria. The theranostic agent can include a small molecule, organic compound capable of aggregation-induced emission and generation of reactive oxygen species upon exposure to white light. The theranostic agent may be used to selectively visualize and/or impair or stop the growth of cancer cells or Gram-positive bacteria in situ during a surgical procedure.

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Inventors:

TANG BENZHONG (CN)
KANG MIAOMIAO (CN)
GU XINGGUI (CN)

Application Number:

PCT/CN2018/087479

Publication Date:

November 22, 2018

Filing Date:

May 18, 2018

Export Citation:

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Assignee:

UNIV HONG KONG SCI & TECH (CN)

International Classes:

C07D215/42; A61K31/438; A61K31/44; A61P31/04; A61P35/00; C07D213/30; C07D215/26; C09K11/06; G01N21/64

Domestic Patent References:

WO2015163817A1	2015-10-29
WO2016070854A1	2016-05-12
WO2016078603A1	2016-05-26

Attorney, Agent or Firm:

TEE & HOWE INTELLECTUAL PROPERTY ATTORNEYS (CN)

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