SUPPLEMENT

CROSS-REFERENCE TO RELATED APPLICATIONS

[01] This application claims the benefit of U.S. Provisional Application No. 62/653,463 filed on April 5, 2018.

FIELD.OF.INVENTIQN

[02] The present invention relates to a method of protecting the respiratory system and liver from continual exposure to environmental contaminants. More specifically, the present invention comprises of prophylactic medical treatment from continual exposure to environmental contaminants by administering herbal mixture of eucalyptus and oregano for respiratory medical conditions and milk thistle for liver medical conditions together with a powerful anti-oxidant Coenzyme Q10 (CoQlO).

BACKGOUNDOF INVENTION

[03] Many individuals around the world are exposed to many environmental contaminants daily through air pollution, foods and drinks contaminated with toxic materials such as pesticides and Other harmful chemicals. Air pollution creates many harmful materials such as ozone (Ok), sulfur dioxide (SOz), nitrogen dioxide (NO2), benzo[a]pyrene and suspended particulate matter (PM). These contaminants are harmful to our important organs causing respiratory disease, cardiovascular disease as well as damage to the liver.

[04] There is a report describing air pollution alone causing around seven million deaths a year worldwide. Considering growth of the population as well as the way in which we consume energy through transportation or heating and air conditioning systems, among others, we do not expect the emission of huge quantities of gases that are harmful to our health would come down. In addition, pathogenic microbes that ran be directly spread through contaminated water cause digestive diseases resulting in 1.5 million deaths each year, mostly in young children. The usual cause of death is dehydration due to diarrhea. Most cases of diarrheal illness and death occur in developing countries because of unsafe water, poor sanitation, and insufficient hygiene. Other waterborne diseases can cause skin infections and organ damage. [ 05] Long-term exposure to polluted air may cause respiratory diseases such as asthma, bronchitis, chronic obstructive pulmonary disease (COPD), emphysema and possibly cancer. Ingested contaminants including viruses may cause liver diseases such as cirrhosis, hepatitis and possibly cancer. In addition, contaminants absorbed into systemic circulation may reach the heart causing heart diseases such as ischemic heart disease and stroke.

[06] Currently there is no viable prophylactic medical treatment option to prevent or reduce the health risk associated with the above environmental contaminants that goes beyond just acute treatment for lung and respiratory diseases and also provides clinical benefits for cardiovascular disease, skin disease as well as damage to the liver. The present invention provides herbal supplement approach to detoxify daily the environmental contaminants absorbed into our body, especially the respiratory system and liver, and strengthen the health of the respiratory system and liver.

SUMMARY OF THE INVENTION

[ 07] The present invention utilizes a mixture of two or more groups of herbs. One group comprises an herb or herbs for protecting the respiratory system (“respiratory herb group”) while the other group comprises an herb or herbs for protecting the liver (“liver herb group”). The mixture can be administered as a form of solid or liquid dosages to detoxify contaminants absorbed into the respiratory system and liver as well as strengthen their health. In a preferred embodiment, the mixture comprises essential oil of milk thistle to protect the liver and a mixture of essential oils of oregano and eucalyptus to protect the respiratory system from environmental contaminations. A third component known as Coenzyme QIO (CoQlO) provides powerful antioxidant effects.

DETAILED DESCRIPTION OF THE INVENTION

[08] Respiratory Herb Group

[09] The respiratory system can be an entry point for various contaminants including harmful chemicals, dust, mold, fungus, harmful organisms and other toxins. These contaminants may cause various respiratory diseases such as asthma, bronchitis, chronic obstructive pulmonary disease (CO PD), emphysema and lung cancer. Unfortunately, currently there is very little prophylactic method for avoiding these serious diseases caused by die contaminants. The inventor believes that nature may provide a number of herbs for detoxifying the contaminants daily and strengthening the respiratory system. These herbs may support the respiratory system by providing the following benefits:

[10] · Breaking up and expelling chest congestion including some contaminants

[11] · Soothing irritated nasal passages and airways

[12] · Relaxing the muscles near the upper respiratory system to reduce a cough

[13] · Reducing the release of histamines

[14] · Fighting the harmful organisms that can cause upper respiratory problems

[15] · Providing source of antioxidants and reducing oxidative damage

[16] Oregano (oreganum vulgare) is mostly known for its use in the kitchen as a spice.

Besides having nutrients that boost the body’s immune system, it also contains two substances, carvacrol and rosmarinic acid, which have anti-histamine and expectorant properties helping to eliminate the uncomfortable buildups of mucus and phlegm in die respiratory tracts and sinuses. It also soothes inflamed lungs and throat, which often cause coughs. The main active ingredient, carvacrol, also has an anti-bacterial and anti-viral effect to prevent bacterial and viral infection. Carvacrol and other active substances in oregano are antioxidants and known to prevent cancer. The present invention can use any form of oregano including dried piece, tea, powder, liquid extract (essential oil) and tincture. In a preferred embodiment, the present invention uses a standardized liquid extract (essential oil ) which contains more than 70% of carvacrol.

[17] Native to Australia, eucalyptus (eucalyptus globulus) has been used to promote respiratory health and soothe throat irritation. Eucalyptus contains cineole which is an expectorant and can ease a cough, fight congestion and soothe sinus passage. Eucalyptus also contains antioxidants which support the immune system during various illnesses. The preseat invention can use any form of eucalyptus including dried piece, tea, powder, liquid extract (essential oil) and tincture. In a preferred embodiment, the present invention uses a standardized liquid extract (essential oil) which contains more than 70% of cineble.

[18] There are many other well-known herbs for detoxifying the contaminants daily and strengthening the respiratory system such as catnip, chaparral, coltsfoot, elecampane, eucalyptus, evening prim rose, hawthorn, horehound, hyssop, lobelia, lungwort, mullein, oregano, osha root, peppermint and plantain leaf.

[19] Liver Herb Group

[20] The liver is actually our largest and important internal organ and responsible for performing a number of essential detoxifying functions. The condition of our blood throughout pur whole body is mostly reliant on the health of our liver. As a blood purifier, the li ver needs to actively clean foe blood constantly in order to support nearly every system within our body. Unfortunately, with ail of foe environmental contaminants which most of us encounter and absorb into our bodies on a daily basis, it is very easy for the liver to become ill itself. For this reason, it is crucial to protect the liver by removing the contaminants out of the liver and subsequently out of the body. There are many herbs known for detoxifying various

contaminants and strengthening foe liver. These herbs may support the liver by providing the following benefits:

[21] · Detoxifying harmful contaminants in the blood including alcohol, pesticides in food supply, heavy metals in water supply and particulate matter (PM) in air pollution

[22 ] · Treating liver diseases including cirrhosis and viral hepatitis

[23] · Providing anti-oxidant effect to remove harmful flee radicals and reduce oxidative stress

[24] Angelica, borututu, chanca piedra, chicory, dandelion, greater celadine, milk thistle, mint, turmeric and yellow dock are natural herbs known for treating the liver diseases and detoxifying various contaminants. [25] Milk thistle ( Silybum mariamm ) has been used over 2,000 years fin ^* treating various diseases related to the liver, kidney and gall bladder. One of the active ingredients in milk thistle is silymarin, a flavonoid known to have antioxidant and anti-inflammatory properties. Si!ymarin and other active substances in milk thistle can protect the liver from environmental contaminants by detoxifying and may help the damaged liver repair itself by promoting the growth of new cells. The main active ingredient (silymarin) is a group of flavonoids consisting of silibinin, silidianin and silicristin. Milk thistle also might lower blood sugar in people who have type 2 diabetes and provide anti-cancer effects. The present invention can use any form of milk thistle including dried piece, tea, powder, liquid extract (essential oil) and tincture. In a preferred embodiment, the present invention uses a standardized liquid extract (essential oil) which contains more than 70% of silymarin.

[26] The present invention combines I - 5 herbs each from die respiratory herb group and liver herb group. The combined herbal mixture can be used for protecting people from environmental contaminants. In a preferred embodiment, the mixture comprises essential oil with active ingredients of milk thistle to protect the liver and a mixture of essential oils with active ingredients of oregano and eucalyptus to protect the respiratory system from

environmental contaminants.

[27] Additional heibal or dietary ingredients may be added to provide extra health benefits. These ingredients include Coenzyme Q 10 (CoQlO), a powerful anti-oxidant, for protecting and strengthening the cardiovascular system and boosting energy. In addition, vitamins and minerals can be added to promote overall wellness and maintain balanced health.

[28] The present invention can use any form of herbal and dietary ingredients including dried piece, tea, powder, liquid extract (essential oil) and tincture. The mixture of these ingredients may be administered in the form of capsules, soft-gels, caplets or tablets in a preferred embodiment, the present invention uses liquid extracts of the ingredients which can be formulated in a soft-gel capsule or other dosage form such as tablet, capsule and caplet [29] For the herbal supplement preparation, the composition of the present invention comprises die ingredients provided in Table 1. Table 1 also describes recommended dose range of each composition and preferred dose per soft-gel capsule after assuming that liquid extract (essential oil) is used for each ingredient The present invention recommends one soft-gel capsule per day, per 8 hours or other timing administration.

[31] It is anticipated by die Applicant that the active ingredients of the herbal supplement in the present invention can be used as an inhalant The inhalant would benefit more acute respiratory conditions and still allow for absorption of the active ingredients of the herbal supplement designed to specifically treatment for the respiratory and liver sequelae due to continual exposure to environmental contaminants including air pollution.