Title:
AMINO ACID SEQUENCES DIRECTED AGAINST THE ANGIOPOIETIN/TIE SYSTEM AND POLYPEPTIDES COMPRISING THE SAME FOR THE TREATMENT OF DISEASES AND DISORDERS RELATED TO ANGIOGENESIS
Document Type and Number:
WIPO Patent Application WO/2010/066836
Kind Code:
A3
Abstract:
The present invention relates to amino acid sequences that are directed against proteins from the group of the Angiopoietin/Tie family such as Tie1, Tie2, Ang1, Ang2, Ang3, Ang4, Angptl1, Angptl12, Angptl13, Angptl14, Angptl15, Angptl16, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more of such amino acid sequences.
Inventors:
GONZALEZ MARIA (PT)
SAUNDERS MICHAEL JOHN SCOTT (BE)
DE HAARD JOHANNES JOSEPH WILHELMUS (NL)
VANLANDSCHOOT PETER (BE)
SAUNDERS MICHAEL JOHN SCOTT (BE)
DE HAARD JOHANNES JOSEPH WILHELMUS (NL)
VANLANDSCHOOT PETER (BE)
Application Number:
PCT/EP2009/066822
Publication Date:
August 05, 2010
Filing Date:
December 10, 2009
Export Citation:
Assignee:
ABLYNX NV (BE)
GONZALEZ MARIA (PT)
SAUNDERS MICHAEL JOHN SCOTT (BE)
DE HAARD JOHANNES JOSEPH WILHELMUS (NL)
VANLANDSCHOOT PETER (BE)
GONZALEZ MARIA (PT)
SAUNDERS MICHAEL JOHN SCOTT (BE)
DE HAARD JOHANNES JOSEPH WILHELMUS (NL)
VANLANDSCHOOT PETER (BE)
International Classes:
C07K16/28
Domestic Patent References:
WO2008089070A2 | 2008-07-24 | |||
WO2005019267A2 | 2005-03-03 | |||
WO2007085815A2 | 2007-08-02 | |||
WO2009147248A2 | 2009-12-10 |
Other References:
REVETS H ET AL: "NANOBODIES AS NOVEL AGENTS FOR CANCER THERAPY", EXPERT OPINION ON BIOLOGICAL THERAPY, ASHLEY, LONDON, GB, vol. 5, no. 1, 1 January 2005 (2005-01-01), pages 111 - 124, XP009076361, ISSN: 1471-2598
See also references of EP 2364328A2
See also references of EP 2364328A2
Attorney, Agent or Firm:
WIEDEMANN, P. (HOFFMANN · EITLE) et al. (München, DE)
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