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Title:
ANTI-PODOPLANIN ANTIBODY AND ANTIBODY-DRUG COMPLEX
Document Type and Number:
WIPO Patent Application WO/2017/026502
Kind Code:
A1
Abstract:
Provided is an anti-podoplanin antibody having high binding activity and effector activity. A human chimera or humanized anti-podoplanin monoclonal antibody having rodent-derived CDR in the variable region and a human-derived constant region, wherein the human chimera or humanized anti-podoplanin monoclonal antibody has a human λ chain constant region in the light chain constant region.

Inventors:
KATO YUKINARI (JP)
KATO MIKA (JP)
NISHIOKA YASUHIKO (JP)
ABE SHINJI (JP)
SANO HIROAKI (JP)
FUJIMOTO OSUKE (JP)
Application Number:
PCT/JP2016/073516
Publication Date:
February 16, 2017
Filing Date:
August 10, 2016
Export Citation:
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Assignee:
UNIV TOHOKU (JP)
UNIV TOKUSHIMA (JP)
FUJIFILM RI PHARMA CO LTD (JP)
International Classes:
C07K16/30; A61K39/395; A61K51/00; A61P13/12; A61P35/00; C12N15/09; C12P21/08
Domestic Patent References:
WO2011040565A12011-04-07
WO2015053381A12015-04-16
Foreign References:
JP2008154468A2008-07-10
US20140017266A12014-01-16
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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