Title:
ARTIFICIAL FIBROIN-DERIVED PROTEIN MOLDED ARTICLE, AND PRODUCTION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2019/189601
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing: an artificial fibroin molded article having improved or modified mechanical characteristics such as elongation at break (stretchability), toughness, tensile strength, and Young's modulus, compared to natural silk; and a method for producing the artificial fibroin molded article. Provided are: a method for producing an artificial fibroin molded article from a silk-doped liquid which is a solution containing a natural or artificial fibroin-derived protein, the method comprising a step for forming an amorphous coagulated product using a cyclic ether solvent as a coagulation bath, or using, as a coagulation bath, a solvent containing a cyclic ether as a coagulating agent, and a step for crystallizing the amorphous coagulated product by performing post-drawing; and an artificial fibroin molded article produced by the production method.
Inventors:
NUMATA KEIJI (JP)
YAZAWA KENJIRO (JP)
IFUKU NAO (JP)
ISHII TAKAOKI (JP)
YAZAWA KENJIRO (JP)
IFUKU NAO (JP)
ISHII TAKAOKI (JP)
Application Number:
PCT/JP2019/013656
Publication Date:
October 03, 2019
Filing Date:
March 28, 2019
Export Citation:
Assignee:
RIKEN (JP)
SPIBER INC (JP)
SPIBER INC (JP)
International Classes:
D01F4/02; C08J3/09; D01D5/06
Other References:
UM, I. C. ET AL.: "Wet spinning of silk polymer I. Effect of coagulation conditions on the morphological feature of filament", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, vol. 34, April 2004 (2004-04-01), pages 89 - 105, XP055178861
KOEPPEL, A. ET AL.: "Progress and trends in artificial silk spinning: A systematic review", ACS BIOMATERIALS SCIENCE & ENGINEERING, vol. 3, 17 January 2017 (2017-01-17), pages 226 - 237, XP055640762
HU , X. ET AL.: "Regulation of silk material structure by temperature-controlled water vapor annealing", BIOMACROMOLECULES, vol. 12, 22 March 2011 (2011-03-22), pages 1686 - 1696, XP055503245, doi:10.1021/bm200062a
KOEPPEL, A. ET AL.: "Progress and trends in artificial silk spinning: A systematic review", ACS BIOMATERIALS SCIENCE & ENGINEERING, vol. 3, 17 January 2017 (2017-01-17), pages 226 - 237, XP055640762
HU , X. ET AL.: "Regulation of silk material structure by temperature-controlled water vapor annealing", BIOMACROMOLECULES, vol. 12, 22 March 2011 (2011-03-22), pages 1686 - 1696, XP055503245, doi:10.1021/bm200062a
Attorney, Agent or Firm:
USHIKI Mamoru (JP)
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