Title:
BEADED POLYETHYLENE GLYCOL-BASED RESINS
Document Type and Number:
WIPO Patent Application WO2003025039
Kind Code:
A3
Abstract:
Described herein is a pentaalkyldisiloxane containing polymeric surfactant prepared by the copolymerization of an alkoxypolyoxyalkylenyl acrylate and an acrylate containing a pentaalkyldisiloxane group. A method for preparing beaded polyethylene glycol-based resins in silicone oil in the presence of a polymeric surfactant containing a pentaalkyldisiloxane group is also described. The average bead size can be controlled by varying the stirring rate, the polymerization temperature, the amount of surfactant, the type of solvent, and the amount of solvent. The surfactant does not interfere with the polymerization and can be removed together with residual silicone oil by a simple washing procedure. The resins can be used, for example, as a support for solid phase organic synthesis, as a chromatographic resin, as a resin for solid phase MAS-NMR spectroscopy, and as a carrier for drug molecules, various reagents, or scavengers.
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Inventors:
GROTLI MORTEN
MELDAL MORTEN PETER
MELDAL MORTEN PETER
Application Number:
PCT/IB2002/005542
Publication Date:
October 23, 2003
Filing Date:
July 09, 2002
Export Citation:
Assignee:
CARLSBERG AS (DK)
International Classes:
C08G65/332; C08L71/02; (IPC1-7): C08F220/28; C08F230/08; A61K9/16; A61K47/48; C08G61/06; C08J3/09
Domestic Patent References:
| WO1998030615A1 | 1998-07-16 |
Foreign References:
| US6156860A | 2000-12-05 | |||
| EP0348106A2 | 1989-12-27 |
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