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Title:
CATIONIC LIPID
Document Type and Number:
WIPO Patent Application WO/2011/136368
Kind Code:
A1
Abstract:
Disclosed is a cationic lipid which is represented by formula (I) and makes it easier to introduce a nucleic acid into a cell. (In formula (I), R1 and R2 may be the same or different and each represents an alkenyl group or the like; X1 and X2 each represents a hydrogen atom, or alternatively X1 and X2 combine together to form a single bond or an alkylene group; X3 is absent or represents an alkyl group or the like; Y is absent or represents an anion; a and b may be the same or different and each represents a number of 0-3; L3 represents a single bond or the like; R3 represents an alkyl group or the like; and L1 and L2 each represents -O-, -CO-O- or -O-CO-.) Also disclosed are: a composition that contains the cationic lipid and a nucleic acid; and a method for introducing a nucleic acid into a cell, using the composition that contains the cationic lipid and a nucleic acid.

Inventors:
KUBOYAMA TAKESHI
ERA TOMOHIRO
NAOI TOMOYUKI
Application Number:
PCT/JP2011/060458
Publication Date:
November 03, 2011
Filing Date:
April 28, 2011
Export Citation:
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Assignee:
KYOWA HAKKO KIRIN CO LTD (JP)
KUBOYAMA TAKESHI
ERA TOMOHIRO
NAOI TOMOYUKI
International Classes:
C07C217/28; A61K47/16; A61K48/00; A61P29/00; A61P35/00; C07C219/20; C07C233/18; C07D207/08; C07D207/12; C12N15/00
Domestic Patent References:
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Foreign References:
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