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Title:
CATIONIC LIPID
Document Type and Number:
WIPO Patent Application WO/2011/136369
Kind Code:
A1
Abstract:
Disclosed is a cationic lipid which is represented by formula (I) and makes it easier to introduce a nucleic acid into a cell. (In formula (I), R1 and R2 may be the same or different and each represents a (Z)-pentadekenyl group, a (Z)-hexadekenyl group, a (Z)-heptadekenyl group or the like; a and b may be the same or different and each represents a number of 0-3; m represents 1; the dotted line represents a single bond or is absent; X1 and X2 each represents a hydrogen atom, or alternatively X1 and X2 combine together to form a single bond or an alkylene group; X4 is absent or represents an alkylene group or the like; X3 is absent or represents an alkyl group or the like; Y is absent or represents an anion; L3 represents a single bond, -CO- or -CO-O-; R3 represents a hydrogen atom, an alkyl group or the like; and L1 and L2 each represents -O-, -CO-O- or -O-CO-.)

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Inventors:
KUBOYAMA TAKESHI
ERA TOMOHIRO
NAOI TOMOYUKI
Application Number:
PCT/JP2011/060459
Publication Date:
November 03, 2011
Filing Date:
April 28, 2011
Export Citation:
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Assignee:
KYOWA HAKKO KIRIN CO LTD (JP)
KUBOYAMA TAKESHI
ERA TOMOHIRO
NAOI TOMOYUKI
International Classes:
A61K9/127; C07C217/28; A61K47/18; A61K47/22; A61K48/00; A61P29/00; A61P35/00; C07D207/12; C12N15/00
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WO1997019675A21997-06-05
WO2005121348A12005-12-22
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