Title:
COMPOSITION FOR INDUCING DEDIFFERENTIATION FROM SOMATIC CELLS TO INDUCED PLURIPOTENT STEM CELLS AND METHOD OF INDUCING DEDIFFERENTIATION USING SAME
Document Type and Number:
WIPO Patent Application WO/2019/194549
Kind Code:
A1
Abstract:
The present invention relates to a composition for inducing dedifferentiation from somatic cells to induced pluripotent stem cells (iPSs) and a method of inducing dedifferentiation using same, wherein the composition for inducing dedifferentiation and the method of inducing dedifferentiation increase the efficiency of dedifferentiation from somatic cells to iPSs by stimulating CXC chemokine receptor 2 (CXCR2), which is a receptor on human somatic cells, and thus may be effectively used for inducing the dedifferentiation to iPSs.
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Inventors:
KIM BYUNG SOO (KR)
LEE SEUNG JIN (KR)
LEE SEUNG JIN (KR)
Application Number:
PCT/KR2019/003898
Publication Date:
October 10, 2019
Filing Date:
April 02, 2019
Export Citation:
Assignee:
UNIV KOREA RES & BUS FOUND (KR)
International Classes:
C12N5/074
Domestic Patent References:
| WO2016076507A1 | 2016-05-19 |
Foreign References:
| KR20110078234A | 2011-07-07 | |||
| KR20170019696A | 2017-02-22 | |||
| US9580682B1 | 2017-02-28 | |||
| US20090047263A1 | 2009-02-19 |
Other References:
BYUNG SOO KIM: "Production of Conditioned Medium Derived front Standardization Human Cell for Complete Feeder Free Culture of Human iPSCs and Its Mechanism Study Ministry of Science and ICT", 13 November 2017 (2017-11-13), pages 1 - 32, XP009524177, Retrieved from the Internet
Attorney, Agent or Firm:
YOON, Dae Woong (KR)
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