Title:
COMPOSITIONS FOR THE ENHANCED TREATMENT OF DEPRESSION
Document Type and Number:
WIPO Patent Application WO2004110417
Kind Code:
A3
Abstract:
For treatment of endogenous depression, there is taken in combination an antidepressant, particularly an SSRI or SNRA, and a precursor or inducer of a neurotransmitter, e.g. L-phenylalanine, tyramine or L-tryptophan. Optionally, the patient also takes vitamin B12.
Inventors:
WORSLEY ANDREW PETER (GB)
Application Number:
PCT/GB2004/002493
Publication Date:
March 24, 2005
Filing Date:
June 11, 2004
Export Citation:
Assignee:
WWK TRUST (GB)
WORSLEY ANDREW PETER (GB)
WORSLEY ANDREW PETER (GB)
International Classes:
A61K31/138; A61K31/343; A61K31/405; A61K31/55; A61K31/714; A61K45/06; (IPC1-7): A61K31/138; A61K45/06; A61K31/55; A61K31/343
Domestic Patent References:
| WO2001085165A2 | 2001-11-15 | |||
| WO2003049687A2 | 2003-06-19 |
Foreign References:
| US6200607B1 | 2001-03-13 | |||
| US6096317A | 2000-08-01 | |||
| EP1112693A1 | 2001-07-04 |
Other References:
DATABASE CHEMABS [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; SENSBA, JUNICHI ET AL: "Evaluation of antidepressant properties of monoamine precursors by the forced-swimming test in mice", XP002297603, retrieved from STN Database accession no. 1988:563333
BECKMANN H ET AL: "DL-PHENYLALANINE IN DEPRESSED PATIENTS: AN OPEN STUDY", JOURNAL OF NEURAL TRANSMISSION, SPRINGER VERLAG, VIENNA, AT, vol. 41, 1977, pages 123 - 134, XP000612721, ISSN: 0300-9564
DATABASE WPI Section Ch Week 200252, Derwent World Patents Index; Class B05, AN 2002-482614, XP002297704
PICKAR D ET AL: "TYRAMINE INFUSIONS IN BI POLAR ILLNESS BEHAVIORAL EFFECTS AND LONGITUDINAL CHANGES IN PRESSOR SENSITIVITY", AMERICAN JOURNAL OF PSYCHIATRY, vol. 136, no. 11, 1979, pages 1460 - 1463, XP008035917, ISSN: 0002-953X
BECKMANN H ET AL: "DL-PHENYLALANINE IN DEPRESSED PATIENTS: AN OPEN STUDY", JOURNAL OF NEURAL TRANSMISSION, SPRINGER VERLAG, VIENNA, AT, vol. 41, 1977, pages 123 - 134, XP000612721, ISSN: 0300-9564
DATABASE WPI Section Ch Week 200252, Derwent World Patents Index; Class B05, AN 2002-482614, XP002297704
PICKAR D ET AL: "TYRAMINE INFUSIONS IN BI POLAR ILLNESS BEHAVIORAL EFFECTS AND LONGITUDINAL CHANGES IN PRESSOR SENSITIVITY", AMERICAN JOURNAL OF PSYCHIATRY, vol. 136, no. 11, 1979, pages 1460 - 1463, XP008035917, ISSN: 0002-953X
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