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Title:
CONTROLLED RELEASE FORMULATION
Document Type and Number:
WIPO Patent Application WO/2019/098300
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a controlled release formulation which can both prevent a compound A from being released precipitously and release the compound A in a pH-independent manner and contains 2-{4-[N-(5,6-diphenylpyradine-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide as an active ingredient. The controlled release formulation is characterized by containing 2-{4-[N-(5,6-diphenylpyradine-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide, a water-soluble polymer, a functionalized starch, and an alkali substance, and having a pH of 10 or more.

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Inventors:
FURUTA SHOUJI (JP)
HATTORI NAOTO (JP)
Application Number:
PCT/JP2018/042359
Publication Date:
May 23, 2019
Filing Date:
November 15, 2018
Export Citation:
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Assignee:
NIPPON SHINYAKU CO LTD (JP)
International Classes:
A61K31/4965; A61K9/20; A61K9/50; A61K47/32; A61K47/36; A61K47/38; A61P1/04; A61P3/10; A61P7/02; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P13/12; A61P17/02; A61P25/00; A61P25/14; A61P43/00
Domestic Patent References:
WO2002088084A12002-11-07
WO2009157398A12009-12-30
WO2017098998A12017-06-15
WO2010150865A12010-12-29
WO2017121806A12017-07-20
WO2017042731A12017-03-16
WO2017029594A12017-02-23
WO2011099573A12011-08-18
WO1998041210A11998-09-24
WO2005005484A12005-01-20
WO2002088084A12002-11-07
WO2009157396A12009-12-30
WO2009107736A12009-09-03
WO2009154246A12009-12-23
WO2009157397A12009-12-30
WO2009157398A12009-12-30
WO2010150865A12010-12-29
WO2017098998A12017-06-15
WO2017029594A12017-02-23
WO2017042731A12017-03-16
WO2018015975A12018-01-25
WO2017040872A12017-03-09
WO2018022704A12018-02-01
WO2018015974A12018-01-25
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JP2014009208A2014-01-20
JP2009506070A2009-02-12
JPS63215620A1988-09-08
JPS62120315A1987-06-01
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See also references of EP 3711763A4
Attorney, Agent or Firm:
NAKAMURA Ayatsugu (JP)
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