Title:
EXOSOME PRODUCTION METHOD
Document Type and Number:
WIPO Patent Application WO/2024/048643
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an exosome production method which makes it possible to produce an exosome with high efficiency. The exosome production method comprises: a step for culturing a cell (12) using a cell fiber (10) comprising a hydrogel (14) having a hollow fiber-like form and the cell (12) encapsulated in the inner cavity of the hydrogel; and a step for collecting an exosome released from the cell (12).
Inventors:
MURAKAMI MAKIKO (JP)
AONO TOSHIYA (JP)
KAWAKAMI YOSHITAKA (JP)
IKEDA KAZUHIRO (JP)
AONO TOSHIYA (JP)
KAWAKAMI YOSHITAKA (JP)
IKEDA KAZUHIRO (JP)
Application Number:
PCT/JP2023/031479
Publication Date:
March 07, 2024
Filing Date:
August 30, 2023
Export Citation:
Assignee:
TOYO BOSEKI (JP)
CELLFIBER CO LTD (JP)
CELLFIBER CO LTD (JP)
International Classes:
C12N5/071; C12M1/00; C12N15/88
Foreign References:
| JP2016077229A | 2016-05-16 |
Other References:
CHEN JIANWEI, ZHOU DUCHAO, NIE ZHENGUO, LU LIANG, LIN ZHIDONG, ZHOU DEZHI, ZHANG YI, LONG XIAOYAN, FAN SIYANG, XU TAO: "A scalable coaxial bioprinting technology for mesenchymal stem cell microfiber fabrication and high extracellular vesicle yield", BIOFABRICATION, INSTITUTE OF PHYSICS PUBLISHING LTD., UK, vol. 14, no. 1, 1 January 2022 (2022-01-01), UK , pages 015012, XP093143487, ISSN: 1758-5082, DOI: 10.1088/1758-5090/ac3b90
CHEN JIACI, LI PEILONG, ZHANG TAIYI, XU ZHIPENG, HUANG XIAOWEN, WANG RUIMING, DU LUTAO: "Review on Strategies and Technologies for Exosome Isolation and Purification", FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, FRONTIERS RESEARCH FOUNDATION, CH, vol. 9, 5 January 2022 (2022-01-05), CH , pages 811971, XP093143492, ISSN: 2296-4185, DOI: 10.3389/fbioe.2021.811971
MUHAMMAD FAIQ ABDULLAH, TAMRIN NUGE, ANDRI ANDRIYANA, BEE CHIN ANG, FARINA MUHAMAD: "Core-Shell Fibers: Design, Roles, and Controllable Release Strategies in Tissue Engineering and Drug Delivery", POLYMERS, vol. 11, no. 12, pages 2008, XP055692343, DOI: 10.3390/polym11122008
CHEN JIACI, LI PEILONG, ZHANG TAIYI, XU ZHIPENG, HUANG XIAOWEN, WANG RUIMING, DU LUTAO: "Review on Strategies and Technologies for Exosome Isolation and Purification", FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, FRONTIERS RESEARCH FOUNDATION, CH, vol. 9, 5 January 2022 (2022-01-05), CH , pages 811971, XP093143492, ISSN: 2296-4185, DOI: 10.3389/fbioe.2021.811971
MUHAMMAD FAIQ ABDULLAH, TAMRIN NUGE, ANDRI ANDRIYANA, BEE CHIN ANG, FARINA MUHAMAD: "Core-Shell Fibers: Design, Roles, and Controllable Release Strategies in Tissue Engineering and Drug Delivery", POLYMERS, vol. 11, no. 12, pages 2008, XP055692343, DOI: 10.3390/polym11122008
Attorney, Agent or Firm:
UNIUS PATENT ATTORNEYS OFFICE (JP)
Download PDF:
Previous Patent: BRAZING DEVICE AND METHOD FOR BRAZING ASSEMBLY
Next Patent: CARRIER, COMPLEX, PHARMACEUTICAL COMPOSITION, AND DIAGNOSTIC DRUG
Next Patent: CARRIER, COMPLEX, PHARMACEUTICAL COMPOSITION, AND DIAGNOSTIC DRUG