FRACTIONATION PRODUCT OF AQUEOUS EXTRACT OF EUCOMMIA ULMOIDES OLIVER LEAF, AND COMPOSITION FOR ORAL INGESTION COMPRISING THE FRACTIONATION PRODUCT

Title:

FRACTIONATION PRODUCT OF AQUEOUS EXTRACT OF EUCOMMIA ULMOIDES OLIVER LEAF, AND COMPOSITION FOR ORAL INGESTION COMPRISING THE FRACTIONATION PRODUCT

Document Type and Number:

WIPO Patent Application WO/2007/102439

Kind Code:

A1

Abstract:

[PROBLEMS] To provide: a fractionation method for extracting an ingredient, particularly a pharmacologically active ingredient such as an iridoid compound, from an Eucommia ulmoides oliver leaf with good efficiency; a fractionation product of anEucommia ulmoides oliver leaf, wherein the fractionation product contains a specific component in a large concentration; and a composition for oral ingestion, pharmaceutical composition, food composition, pharmaceutical or food which comprises a natural material as a raw material, produces little adverse side effects, and is safe even when ingested over a long period. [MEANS FOR SOLVING PROBLEMS] Disclosed is a fractionation product of an aqueous extract of an Eucommia ulmoides oliver leaf. The fractionation product can be produced by a process comprising the step of adsorbing an aqueous extract of an Eucommia ulmoides oliver leaf onto a reverse-phase synthetic adsorbent to yield a component which can be eluted with water, wherein the aqueous extract is prepared from a dried Eucommia ulmoides oliver leaf. Also disclosed is a pharmaceutical or food comprising the fractionation product.

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Inventors:

HIRATA TETSUYA (JP)

Application Number:

PCT/JP2007/054086

Publication Date:

September 13, 2007

Filing Date:

March 02, 2007

Export Citation:

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Assignee:

KOBAYASHI PHARMA (JP)
HIRATA TETSUYA (JP)

International Classes:

A61K36/46; A23L1/30; A23L2/38; A61K9/20; A61K31/7048; A61K36/00; A61P3/04; A61P3/06; A61P3/10; A61P9/12; A61P43/00; C07H17/04

Domestic Patent References:

WO2005099488A1	2005-10-27
WO2005099734A1	2005-10-27

Foreign References:

JPH10304848A	1998-11-17
JPH04368336A	1992-12-21
JPH09248163A	1997-09-22

Other References:

NAKAZATO M. ET AL.: "Tochuba o Shugenryo to shita Kenko Shokuhinchu no Geniposide san Oyobi Caffeine no Bunseki", SHOKUHIN EISEIGAKU ZASSHI, vol. 37, no. 6, 1996, pages 343 - 350, XP003017655

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