Title:
GLUCAGON ANALOG AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/262837
Kind Code:
A1
Abstract:
A glucagon analog and the medical use thereof. Specifically, the glucagon analog has a significantly improved in vitro activity, excellent physical/chemical stability, and high solubility, and can be used to treat metabolic diseases such as hypoglycemia, obesity, and diabetes.
Inventors:
LIU WEIBING (CN)
HUANG XUCHAO (CN)
ZHANG XIAOQIAN (CN)
WU FANGZHOU (CN)
WANG LEI (CN)
QU LIANG (CN)
HUANG XUCHAO (CN)
ZHANG XIAOQIAN (CN)
WU FANGZHOU (CN)
WANG LEI (CN)
QU LIANG (CN)
Application Number:
PCT/CN2022/099357
Publication Date:
December 22, 2022
Filing Date:
June 17, 2022
Export Citation:
Assignee:
BEIJING TUO JIE BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07K14/605; A61K38/26; A61P3/10
Domestic Patent References:
| WO2014016300A1 | 2014-01-30 | |||
| WO2015185640A1 | 2015-12-10 | |||
| WO2013098408A1 | 2013-07-04 | |||
| WO2013192129A1 | 2013-12-27 | |||
| WO2020163125A1 | 2020-08-13 | |||
| WO2019101035A1 | 2019-05-31 | |||
| WO2012153196A2 | 2012-11-15 | |||
| WO1998011125A1 | 1998-03-19 |
Foreign References:
| CN202110676681A | 2021-06-18 |
Other References:
J. BIOL. CHEM., vol. 243, 1968, pages 3558
PAULI-MAGNUS C ET AL., J PHARMACOL EXP THEN, vol. 293, no. 2, May 2000 (2000-05-01), pages 376 - 82
PAULI-MAGNUS C ET AL., J PHARMACOL EXP THEN, vol. 293, no. 2, May 2000 (2000-05-01), pages 376 - 82
Attorney, Agent or Firm:
GE CHENG & CO., LTD (CN)
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