GUANIDINE DERIVATIVES AS INHIBITORS OF DDAH

Title:

GUANIDINE DERIVATIVES AS INHIBITORS OF DDAH

Document Type and Number:

WIPO Patent Application WO2006051314

Kind Code:

A8

Abstract:

Compounds of formula (I) have been found to be useful as inhibitors of DDAH. The present invention thus provides the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for use in the treatment of a disease whose pathology is affected by DDAH.

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Inventors:

VALLANCE PATRICK JOHN THOMPSON (GB)
LEIPER JAMES MITCHELL (GB)
SELWOOD DAVID LAWRENCE (GB)
ROSSITER SHARON (GB)
HARTZOULAKIS BASIL (GB)

Application Number:

PCT/GB2005/004361

Publication Date:

September 28, 2006

Filing Date:

November 11, 2005

Export Citation:

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Assignee:

UCL BIOMEDICA PLC (GB)
VALLANCE PATRICK JOHN THOMPSON (GB)
LEIPER JAMES MITCHELL (GB)
SELWOOD DAVID LAWRENCE (GB)
ROSSITER SHARON (GB)
HARTZOULAKIS BASIL (GB)

International Classes:

C07C279/14; A61K31/16; A61K31/198; A61K31/223; A61K31/40; A61K31/4453; A61K31/5375; A61P9/10; A61P11/06; A61P19/02; C07C279/16; C07C279/18; C07C323/44; C07D295/215

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