HETEROLOGOUS PRODUCTION OF POLYKETIDES

Title:

HETEROLOGOUS PRODUCTION OF POLYKETIDES

Document Type and Number:

WIPO Patent Application WO2001083800

Kind Code:

A9

Abstract:

Recombinant Myxococcus host cells can be used to produce polyketides, including epothilone and epothilone analogs that can be purified from the fermentation broth and crystallized.

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Inventors:

ARSLANIAN ROBERT L (US)
ASHLEY GARY (US)
FRYKMAN SCOTT (US)
JULIEN BRYAN (US)
KATZ LEONARD (US)
KHOSLA CHAITAN (US)
LAU JANICE (US)
LICARI PETER J (US)
REGENTIN RIKA (US)
SANTI DANIEL (US)
TANG LI (US)

Application Number:

PCT/US2001/013793

Publication Date:

September 12, 2003

Filing Date:

April 26, 2001

Export Citation:

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Assignee:

KOSAN BIOSCIENCES INC (US)
ARSLANIAN ROBERT L (US)
ASHLEY GARY (US)
FRYKMAN SCOTT (US)
JULIEN BRYAN (US)
KATZ LEONARD (US)
KHOSLA CHAITAN (US)
LAU JANICE (US)
LICARI PETER J (US)
REGENTIN RIKA (US)
SANTI DANIEL (US)
TANG LI (US)

International Classes:

C07D313/00; C07D405/06; C07D413/06; C07D417/06; C07D491/04; C12N1/20; C12N1/21; C12N9/00; C12N15/52; C12N15/74; C12P17/16; C12P17/18; C12R1/01; (IPC1-7): C12N15/52; C12N15/74; C12N9/00; C12N1/21; C12P17/16; C12P17/18; C07D313/00; C07D413/06; C07D417/06; C07D493/04; C07D493/06

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