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Title:
HIGHLY SENSITIVE IMMUNOLOGICAL ANALYSIS METHOD AND IMMUNOLOGICAL ANALYSIS REAGENT FOR HEPATITIS B VIRUS
Document Type and Number:
WIPO Patent Application WO/2008/053900
Kind Code:
A1
Abstract:
The object is to provide: a highly sensitive immunological analysis method for a hepatitis B virus; a highly sensitive immunological analysis reagent for a hepatitis B virus; and an immunological analysis kit for a hepatitis B virus, each of which utilizes an antigen-antibody reaction. The object is achieved by conducting an antigen/antibody reaction in which an antigen is contacted with an antibody in the presence of a saponin, a bile salt or an anionic surfactant. Specifically disclosed is an immunological analysis method for a hepatitis B virus by a sandwich method involving the step of contacting an antigen with a soluble antibody, wherein a saponin, a bile salt or an anionic surfactant is preferably allowed to exist in the reaction system. Further disclosed are: a highly sensitive immunological analysis reagent for a hepatitis B virus; and an immunological analysis kit for a hepatitis B virus, each of which utilizes an antigen-antibody reaction.

Inventors:
MATSUBARA NAOKO (JP)
SUGAMATA YASUHIRO (JP)
KUSANO OSAMU (JP)
SHIRATA NORIKO (JP)
Application Number:
PCT/JP2007/071149
Publication Date:
May 08, 2008
Filing Date:
October 30, 2007
Export Citation:
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Assignee:
ADVANCED LIFE SCIENCE INST INC (JP)
MATSUBARA NAOKO (JP)
SUGAMATA YASUHIRO (JP)
KUSANO OSAMU (JP)
SHIRATA NORIKO (JP)
International Classes:
G01N33/531; G01N33/543; G01N33/576
Foreign References:
JP2002277472A2002-09-25
JP2000105233A2000-04-11
Attorney, Agent or Firm:
MORITA, Kenichi (Itabashi-chuo Bldg. 67-8, Itabashi 2-chome, Itabashi-k, Tokyo 04, JP)
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