HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS

Title:

HYDRAZIDE DERIVATIVES AS PROSTAGLANDIN RECEPTORS MODULATORS

Document Type and Number:

WIPO Patent Application WO2005012232

Kind Code:

A3

Abstract:

The present invention relates to hydrazide derivatives of Formula (I) notably for use as pharmaceutically active compounds, as well as to pharmaceutical formulations containing such hydrazide derivatives. Said hydrazide derivatives are useful in the treatment of preterm labor, dysmenorrhea, fertility disorders, asthma, hypertension, undesired blood clotting, preelampsia, eclampsia, an eosinophil disorder, undesired bone loss, renal dysfunction, an immune deficiency disorder, ichthyosis, elevated intraocular pressure, infertility, sexual dysfunction, gastric ulcers and inflammatory disorders.

Inventors:

ARALDI GIAN LUCA (US)
LIAO YIHUA (US)
BRUGGER NADIA (US)

Application Number:

PCT/EP2004/051531

Publication Date:

March 31, 2005

Filing Date:

July 16, 2004

Export Citation:

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Assignee:

APPLIED RESEARCH SYSTEMS (NL)
ARALDI GIAN LUCA (US)
LIAO YIHUA (US)
BRUGGER NADIA (US)

International Classes:

A61P19/10; C07C243/28; C07D333/16; (IPC1-7): C07C243/28; A61K31/16; A61P19/10

Domestic Patent References:

WO2001046140A1

2001-06-28

Foreign References:

US6235780B1	2001-05-22
US5281590A	1994-01-25

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