Title:
IN VITRO PROCEDURE FOR DIAGNOSIS AND EARLY DIAGNOSIS OF NEURODEGENERATIVE DISEASES
Document Type and Number:
WIPO Patent Application WO2007131775
Kind Code:
A8
Abstract:
An in vitro process for the detection and early detection of neurodegenerative diseases, for determination of the severity, and to evaluate the progression of and render a prognoses of neurogenerative diseases, in a patient suffering from a subjectively or objectively detectable cognitive impairment, by determining the concentration of an analyte selected from natriuretic peptides, in particular ANP, and, if necessary, BNP and/or CNP in a biological fluid of the patient, whereby the determination of the analyte is performed directly and/or indirectly as the determination of a relevant co-peptide generated from a mutual propeptide, and is based upon the measured concentration of the determined analyte thus making it possible to form conclusions about a neurodegenerative disease or an early form typical of such a disease or the course of the disease and/or the success of the efforts to relieve or prevent the disease.
Inventors:
BERGMANN ANDREAS (DE)
ERNST ANDREA (DE)
HAMPEL HARALD (DE)
ERNST ANDREA (DE)
HAMPEL HARALD (DE)
Application Number:
PCT/EP2007/004314
Publication Date:
March 20, 2008
Filing Date:
May 15, 2007
Export Citation:
Assignee:
BRAHMS AG (DE)
BERGMANN ANDREAS (DE)
ERNST ANDREA (DE)
HAMPEL HARALD (DE)
BERGMANN ANDREAS (DE)
ERNST ANDREA (DE)
HAMPEL HARALD (DE)
International Classes:
G01N33/68
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