Title:
LIVER DISEASE MARKER, METHOD AND APPARATUS FOR MEASURING SAME, AND TEST METHOD FOR PHARMACEUTICAL PREPARATION
Document Type and Number:
WIPO Patent Application WO/2011/158590
Kind Code:
A1
Abstract:
Disclosed is a method for promptly identifying a liver disease. A normal person (C) or a liver disease such as drug-induced liver injury (DI), asymptomatic hepatitis B carrier (AHB), chronic hepatitis B (CHB), hepatitis C with persistently normal ALT (CNALT), chronic hepatitis C (CHC), cirrhosis type C (CIR), hepatocellular carcinoma (HCC), simple steatosis (SS), or non-alcoholic steatohepatitis (NASH) is identified by measuring the concentration of a γ-Glu-X (wherein X represents an amino acid or an amine) peptide or the level of AST or ALT in blood and carrying out, for example, a multiple logistic regression (MLR) based on the measured value.
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Inventors:
SOGA TOMOYOSHI (JP)
SUGIMOTO MASAHIRO (JP)
SUEMATSU MAKOTO (JP)
SAITO TAKAFUMI (JP)
KAWATA SUMIO (JP)
SUGIMOTO MASAHIRO (JP)
SUEMATSU MAKOTO (JP)
SAITO TAKAFUMI (JP)
KAWATA SUMIO (JP)
Application Number:
PCT/JP2011/061340
Publication Date:
December 22, 2011
Filing Date:
May 17, 2011
Export Citation:
Assignee:
UNIV KEIO (JP)
SOGA TOMOYOSHI (JP)
SUGIMOTO MASAHIRO (JP)
SUEMATSU MAKOTO (JP)
SAITO TAKAFUMI (JP)
KAWATA SUMIO (JP)
SOGA TOMOYOSHI (JP)
SUGIMOTO MASAHIRO (JP)
SUEMATSU MAKOTO (JP)
SAITO TAKAFUMI (JP)
KAWATA SUMIO (JP)
International Classes:
G01N33/15; G01N33/68; G01N33/50
Domestic Patent References:
| WO2007083632A1 | 2007-07-26 | |||
| WO2010073870A1 | 2010-07-01 | |||
| WO2010091290A1 | 2010-08-12 |
Attorney, Agent or Firm:
TAKAYA, Satoshi et al. (JP)
High arrow 諭 (JP)
High arrow 諭 (JP)
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Claims: