Title:
MEDICAL USE OF BENZENESULFONAMIDE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/068951
Kind Code:
A1
Abstract:
A medical use of a benzenesulfonamide compound and a pharmaceutical composition thereof. In particular, the present invention relates to a compound represented by one of formulas I to V or a pharmaceutically acceptable salt or solvate thereof. The present invention can be used to prepare a STING inhibitor or a drug for inhibiting the activation of STING signaling pathway and to prepare a drug for preventing or treating a disease mediated by STING.
Inventors:
WANG CHEN (CN)
HONG ZE (CN)
YU WENYING (CN)
SUN HONGBIN (CN)
MEI JIAHAO (CN)
LI CHENHUI (CN)
LIU XING (CN)
SUN LI (CN)
LIU JUN (CN)
HONG ZE (CN)
YU WENYING (CN)
SUN HONGBIN (CN)
MEI JIAHAO (CN)
LI CHENHUI (CN)
LIU XING (CN)
SUN LI (CN)
LIU JUN (CN)
Application Number:
PCT/CN2020/120280
Publication Date:
April 15, 2021
Filing Date:
October 12, 2020
Export Citation:
Assignee:
UNIV CHINA PHARMA (CN)
International Classes:
A61K31/18; A61P1/16; A61P3/10; A61P9/00; A61P9/10; A61P17/06; A61P19/02; A61P29/00; A61P37/02
Domestic Patent References:
| WO2012027392A2 | 2012-03-01 | |||
| WO2002024636A2 | 2002-03-28 |
Foreign References:
| US20090163545A1 | 2009-06-25 | |||
| US20120196865A1 | 2012-08-02 | |||
| US20110275663A1 | 2011-11-10 | |||
| CN105579457A | 2016-05-11 |
Other References:
STEFAN HINSBERGER, KRISTINA H�SECKEN, MATTHIAS GROH, MATTHIAS NEGRI, J�RG HAUPENTHAL, ROLF W. HARTMANN: "Discovery of Novel Bacterial RNA Polymerase Inhibitors: Pharmacophore-Based Virtual Screening and Hit Optimization", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 56, no. 21, 14 November 2013 (2013-11-14), US, pages 8332 - 8338, XP055378011, ISSN: 0022-2623, DOI: 10.1021/jm400485e
Attorney, Agent or Firm:
NANJING SUGAO PATENT AND TRADEMARK FIRM ( ORDINARY PARTNERSHIP ) (CN)
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