Title:
METHOD FOR AIDING DETECTION OF PANCREATIC CANCER
Document Type and Number:
WIPO Patent Application WO/2019/117269
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a method for aiding highly accurate detection of pancreatic cancer. The present invention provides a method for aiding the detection of pancreatic cancer that uses, as an indicator, the amount present in a test sample isolated from a living subject of at least one molecule from among an miRNA, an isoform (isomiR) thereof, an miRNA precursor, a transfer RNA fragment (tRF), or a non-coding RNA fragment (MiscRNA) for which the base sequence is identified by any sequence from among SEQ ID NOs: 1, 4, 6–10, 12, 15, 17, 19–21, 2, 3, 5, 11, 13, 14, 16, 18, and 22–38, wherein when the amount of at least one miRNA, isomiR, miRNA precursor, or transfer RNA fragment for which the base sequence is identified by any sequence from among SEQ ID NOs: 1–20 is higher than that of a healthy subject, or when the amounts of miRNAs, isomiRs, miRNA precursors, or non-coding RNA fragments (MiscRNAs) for which the base sequences are SEQ ID NOs: 21–38 are lower than those of a healthy subject, there is a high possibility of developing pancreatic cancer.
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Inventors:
TAHARA HIDETOSHI (JP)
Application Number:
PCT/JP2018/045993
Publication Date:
June 20, 2019
Filing Date:
December 13, 2018
Export Citation:
Assignee:
UNIV HIROSHIMA (JP)
International Classes:
C12N15/113; C12Q1/68; G01N33/50
Domestic Patent References:
| WO2015182781A1 | 2015-12-03 | |||
| WO2014003053A1 | 2014-01-03 | |||
| WO2015133477A1 | 2015-09-11 | |||
| WO2015091897A1 | 2015-06-25 | |||
| WO2014003053A1 | 2014-01-03 |
Foreign References:
| JP2009521952A | 2009-06-11 | |||
| JP2009528070A | 2009-08-06 | |||
| JP2015502176A | 2015-01-22 | |||
| US20150011414A1 | 2015-01-08 | |||
| JP2009521952A | 2009-06-11 | |||
| JP2009528070A | 2009-08-06 | |||
| JP2010527235A | 2010-08-12 |
Attorney, Agent or Firm:
TANIGAWA AND PARTNERS, PATENT FIRM (JP)
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