METHOD FOR IMPROVING BIOAVAILABILITY OF LATANOPROST

Title:

METHOD FOR IMPROVING BIOAVAILABILITY OF LATANOPROST

Document Type and Number:

WIPO Patent Application WO/2011/001634

Kind Code:

A1

Abstract:

The present invention relates to a method for improving ocular bioavailability of latanoprost by adding an organic amine to an aqueous eye drop composition containing latanoprost. The invention further relates to an aqueous eye drop composition in which a better ocular bioavailability of latanoprost is achieved by adding an organic amine, and to a method for treating ocular hypertension and glaucoma by administering said composition to a subject in need of such treatment.

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Inventors:

REUNAMAKI TIMO (FI)
TERVO PAULA (FI)
LOKKILA JUKKA (FI)
PELLINEN PERTTI (FI)
ALAJUUMA PAIVI (FI)
OKSALA OLLI (FI)

Application Number:

PCT/JP2010/004179

Publication Date:

January 06, 2011

Filing Date:

June 23, 2010

Export Citation:

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Assignee:

SANTEN PHARMACEUTICAL CO LTD (JP)
REUNAMAKI TIMO (FI)
TERVO PAULA (FI)
LOKKILA JUKKA (FI)
PELLINEN PERTTI (FI)
ALAJUUMA PAIVI (FI)
OKSALA OLLI (FI)

International Classes:

A61K31/5575; A61J1/05; A61K9/08; A61K47/18; A61K47/32; A61K47/38; A61P27/06

Domestic Patent References:

WO2008096804A1	2008-08-14
WO2007015510A1	2007-02-08

Foreign References:

JP2009040749A

2009-02-26

Other References: