Title:
METHOD FOR PREPARING NOVEL CHITOSAN OLIGOSACCHARIDE COMPOSITION AND CHITOSAN OLIGOSACCHARIDE MIXTURE PREPARED THEREBY
Document Type and Number:
WIPO Patent Application WO/2014/126379
Kind Code:
A1
Abstract:
The present invention provides a method for preparing a chitosan oligosaccharide composition which increases the content of chitosan disaccharide having excellent effects in reducing the glycated hemoglobin level and blood glucose level and has excellent thermal stability. The method for preparing a chitosan oligosaccharide composition of the present invention comprises the steps of: adding chitosan into distilled water to swell the chitosan; first treating the chitosan with chitosanase to prevent a chitosan solution from being viscous, and then adding an organic acid to a mixture solution of the chitosan and the chitonase in multiple portions at intervals of time; allowing the chitosan, the chitosanase, and the organic acid to react with one another; and inactivating the chitosanase and obtaining a chitosan oligosaccharide composition. Further, the present invention provides a medicinal product or a health functional food which is devoid of monosaccharide, has at least 40 wt% of disaccharide, shows excellent effects in reducing the glycated hemoglobin level and blood glucose level in patients with type 2 diabetes, and thus is effective in the prevention and treatment of diabetes.
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Inventors:
OH CHEN GUM (KR)
KWON YOUNG IN (KR)
LEE JONG WOOK (KR)
KIM SEONG CHUL (KR)
KWON YOUNG IN (KR)
LEE JONG WOOK (KR)
KIM SEONG CHUL (KR)
Application Number:
PCT/KR2014/001137
Publication Date:
August 21, 2014
Filing Date:
February 12, 2014
Export Citation:
Assignee:
KUNPOONG BIO CO LTD (KR)
International Classes:
A61K31/70; A61K31/722; A61P9/00; A61P9/12
Foreign References:
| KR100506710B1 | 2005-08-05 | |||
| EP1659182A1 | 2006-05-24 |
Other References:
GARRY KERCH ET AL.: "The effect of chitosan oligosaccharides on bread staling.", JOURNAL OF CEREAL SCIENCE ., vol. 52, no. 3, November 2010 (2010-11-01), pages 491 - 495, XP027527183
Attorney, Agent or Firm:
SHIN, Jin Man (KR)
신진만 (KR)
신진만 (KR)
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