Title:
METHOD FOR PREPARING TICAGRELOR AND NOVEL INTERMEDIATES THEREFOR
Document Type and Number:
WIPO Patent Application WO/2016/117852
Kind Code:
A3
Abstract:
The present invention relates to a novel method for preparing ticagrelor, (1S, 2S, 3R, 5S)-3-[7-[(1R, 2S)-2-(3,4-difluorophenyl)cyclopropylamino]-5-(propylthio)-3H-[l,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol, which is represented by the following chemical formula (1), and novel intermediates used therefor. The present invention allows ticagrelor to be easily prepared from the novel intermediates:
Inventors:
KIM HOO SOOK (KR)
KIM JAEHAN (KR)
KIM YONG JIK (KR)
KWAK WOO YOUNG (KR)
LIM JOONG IN (KR)
CHA DAE-WON (KR)
SHIN CHANG YONG (KR)
KIM JAEHAN (KR)
KIM YONG JIK (KR)
KWAK WOO YOUNG (KR)
LIM JOONG IN (KR)
CHA DAE-WON (KR)
SHIN CHANG YONG (KR)
Application Number:
PCT/KR2016/000102
Publication Date:
October 27, 2016
Filing Date:
January 06, 2016
Export Citation:
Assignee:
DONG A ST CO LTD (KR)
International Classes:
C07D487/04; C07D487/02; C07F5/02
Domestic Patent References:
| WO2013163892A1 | 2013-11-07 | |||
| WO2012138981A2 | 2012-10-11 | |||
| WO2014086291A1 | 2014-06-12 |
Foreign References:
| KR20080003458A | 2008-01-07 | |||
| US20130165696A1 | 2013-06-27 |
Attorney, Agent or Firm:
YOU ME PATENT & LAW FIRM (Gangnam-gu, Seoul, KR)
Download PDF:
Previous Patent: METAL-BONDED SUBSTRATE
Next Patent: MTJ STRUCTURE HAVING VERTICAL MAGNETIC ANISOTROPY AND MAGNETIC ELEMENT INCLUDING SAME
Next Patent: MTJ STRUCTURE HAVING VERTICAL MAGNETIC ANISOTROPY AND MAGNETIC ELEMENT INCLUDING SAME