Title:
METHOD FOR PRODUCING CELL CONCENTRATE
Document Type and Number:
WIPO Patent Application WO/2014/034456
Kind Code:
A1
Abstract:
Provided is a simple method for producing a cell concentrate (excluding human blood) in little time, without losing cells and without burdening superfluous cells. Provided is a method for producing a cell concentrate, the method using a cell suspension processor which is an internal pressure filtration format provided with a cell suspension inlet, a filtrate outlet, a cell suspension outlet, and a hollow-fiber separation membrane arranged between the cell suspension inlet and the cell suspension outlet; the method being characterized in that the total cross-sectional area of the hollow-fiber separation membrane is 0.5 to 1.5 cm2, the inside membrane area of the hollow-fiber separation membrane is 0.2 m2 or less, the linear speed of flow through the interior of the hollow-fiber separation membrane is 500 to 1200 cm/min, and the value found by dividing the initial filtration flow rate discharged from the filtrate outlet by the flow rate into the cell suspension inlet is 0.4 to 0.7.
Inventors:
TANIGUCHI SHUHEI (JP)
Application Number:
PCT/JP2013/072056
Publication Date:
March 06, 2014
Filing Date:
August 19, 2013
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
C12N1/00; B01D61/14; B01D63/02; B01D69/08; B01D71/10; B01D71/68; C12N5/078
Domestic Patent References:
| WO2013061859A1 | 2013-05-02 | |||
| WO2012090863A1 | 2012-07-05 |
Foreign References:
| JP2006305333A | 2006-11-09 | |||
| JP2006129987A | 2006-05-25 | |||
| JP2005336080A | 2005-12-08 | |||
| JP2007524396A | 2007-08-30 | |||
| JP2928913B2 | 1999-08-03 |
Other References:
CASTINO F. ET AL.: "Washing frozen red blood cell concentrates using hollow fibres.", JOURNAL OF MEMBRANE SCIENCE, vol. 110, 1996, pages 169 - 180, XP004041725
See also references of EP 2891710A4
See also references of EP 2891710A4
Attorney, Agent or Firm:
YASUTOMI & Associates (JP)
Patent business corporation Yasutomi international patent firm (JP)
Patent business corporation Yasutomi international patent firm (JP)
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