Title:
METHOD FOR PRODUCING OPTICALLY ACTIVE 1,1,3-TRIMETHYL-4-AMINOINDANE
Document Type and Number:
WIPO Patent Application WO/2022/014413
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a novel method for producing optically active 1,1,3-trimethyl-4-aminoindane by means of a preferential crystallization method using an achiral acid and without using an optically active acid. The present invention provides a method for producing optically active 1,1,3-trimethyl-4-aminoindane, the method including: a first step for mixing optically active 1,1,3-trimethyl-4-aminoindane and an achiral acid in the presence of a solvent so as to precipitate an acid salt of these; and a second step for mixing the acid salt obtained in the first step with a base so as to obtain optically active 1,1,3-trimethyl-4-aminoindane.
Inventors:
HAGIYA KOJI (JP)
Application Number:
PCT/JP2021/025488
Publication Date:
January 20, 2022
Filing Date:
July 06, 2021
Export Citation:
Assignee:
SUMITOMO CHEMICAL CO (JP)
International Classes:
C07C209/88; C07B57/00; C07C211/60; C07D231/14
Domestic Patent References:
| WO2015118793A1 | 2015-08-13 |
Foreign References:
| JP2010513316A | 2010-04-30 | |||
| JPS6210066A | 1987-01-19 | |||
| JPH04108774A | 1992-04-09 |
Attorney, Agent or Firm:
NAKAYAMA, Tohru et al. (JP)
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